Tetsuaki Hiyoshi
Fujisawa, Japan
Last Updated: 09/26/2026
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Found 12 publications
Characterization of a humanized mouse model of Charcot-Marie-Tooth type 1A for the discovery of human PMP22-targeting drugs.
Journal: Frontiers in neurology
Published: July 02, 2025
Electrical impedance myography detects progressive pathological alterations in the hindlimb muscle of the PMP22-C3 mice, an animal model of CMT1A.
Journal: Experimental neurology
Published: September 17, 2024
TAK-861, a potent, orally available orexin receptor 2-selective agonist, produces wakefulness in monkeys and improves narcolepsy-like phenotypes in mouse models.
Journal: Scientific reports
Published: May 15, 2024
Electrical impedance myography detects dystrophin-related muscle changes in mdx mice.
Journal: Skeletal muscle
Published: August 29, 2023
Discovery of ORN0829, a potent dual orexin 1/2 receptor antagonist for the treatment of insomnia.
Journal: Bioorganic & medicinal chemistry
Published: March 05, 2020
Development, validation, and application of a surrogate analyte method for determining N-acetyl-l-aspartyl-l-glutamic acid levels in rat brain, plasma, and cerebrospinal fluid.
Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences
Published: June 24, 2015
Antipsychotic profiles of TASP0443294, a novel and orally active positive allosteric modulator of metabotropic glutamate 2 receptor.
Journal: Journal of pharmacological sciences
Published: January 08, 2015
Neurophysiologic and antipsychotic profiles of TASP0433864, a novel positive allosteric modulator of metabotropic glutamate 2 receptor.
Journal: The Journal of pharmacology and experimental therapeutics
Published: October 04, 2014
Involvement of glutamatergic and GABAergic transmission in MK-801-increased gamma band oscillation power in rat cortical electroencephalograms.
Journal: Neuroscience
Published: June 20, 2014
Differential effects of NMDA receptor antagonists at lower and higher doses on basal gamma band oscillation power in rat cortical electroencephalograms.
Journal: Neuropharmacology
Published: March 15, 2014
Metabotropic glutamate receptors regulate cortical gamma hyperactivities elicited by ketamine in rats.
Journal: Neuroscience letters
Published: January 28, 2014
Discovery of novel antipsychotics targeting group II metabotropic glutamate receptor
Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica
Published: September 15, 2012
Showing 1-12 of 12
Last Updated: 09/26/2026