Thiago L. Souza

Rio De Janeiro, RJ 21040900, Brazil

Last Updated: 09/26/2026

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Found 24 publications

Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent HsDHODH Inhibitors with Optimized Properties.

Quinazolinones as Bioisosteres of Naphthoquinones: A Path to Potent HsDHODH Inhibitors with Optimized Properties.

Journal: ACS medicinal chemistry letters

Published: April 28, 2025

Targeting dihydroorotate dehydrogenase (DHODH) for host-directed therapy: Discovery of a novel alkyne-based scaffold inhibitor effective against SARS-CoV-2.

Targeting dihydroorotate dehydrogenase (DHODH) for host-directed therapy: Discovery of a novel alkyne-based scaffold inhibitor effective against SARS-CoV-2.

Journal: European journal of medicinal chemistry

Published: January 26, 2025

The role of the P2X7 receptor in inactivated SARS-CoV-2-induced lung injury.

The role of the P2X7 receptor in inactivated SARS-CoV-2-induced lung injury.

Journal: Purinergic signalling

Published: August 09, 2024

Enhanced Assessment of Cross-Reactive Antigenic Determinants within the Spike Protein.

Enhanced Assessment of Cross-Reactive Antigenic Determinants within the Spike Protein.

Journal: International journal of molecular sciences

Published: June 05, 2024

Metabolic reprogramming and lipid droplets are involved in Zika virus replication in neural cells.

Metabolic reprogramming and lipid droplets are involved in Zika virus replication in neural cells.

Journal: Journal of neuroinflammation

Published: October 25, 2022

Severe influenza infection is associated with inflammatory programmed cell death in infected macrophages.

Severe influenza infection is associated with inflammatory programmed cell death in infected macrophages.

Journal: Frontiers in cellular and infection microbiology

Published: October 11, 2022

Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn trial.

Antivirals for adult patients hospitalised with SARS-CoV-2 infection: a randomised, phase II/III, multicentre, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn trial.

Journal: Lancet regional health. Americas

Published: October 11, 2022

Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating.

Inhibition of SARS-CoV-2 infection in human iPSC-derived cardiomyocytes by targeting the Sigma-1 receptor disrupts cytoarchitecture and beating.

Journal: PeerJ

Published: September 30, 2021

Multiepitope Proteins for the Differential Detection of IgG Antibodies against RBD of the Spike Protein and Non-RBD Regions of SARS-CoV-2.

Multiepitope Proteins for the Differential Detection of IgG Antibodies against RBD of the Spike Protein and Non-RBD Regions of SARS-CoV-2.

Journal: Vaccines

Published: June 20, 2021

SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites.

SARS-CoV-2 Proteins Bind to Hemoglobin and Its Metabolites.

Journal: International journal of molecular sciences

Published: June 18, 2021

WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2.

WIN 55,212-2 shows anti-inflammatory and survival properties in human iPSC-derived cardiomyocytes infected with SARS-CoV-2.

Journal: PeerJ

Published: June 15, 2021

Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency.

Polyclonal F(ab')2 fragments of equine antibodies raised against the spike protein neutralize SARS-CoV-2 variants with high potency.

Journal: iScience

Published: May 12, 2021

Showing 1-12 of 24

Last Updated: 09/26/2026