Thierry Bertomeu

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 27 publications

The scaffold protein PRR14L is linked to mitotic fidelity and sensitivity to MPS1 inhibition.

The scaffold protein PRR14L is linked to mitotic fidelity and sensitivity to MPS1 inhibition.

Journal: Molecular biology of the cell

Published: May 20, 2026

The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.

The role of ATP synthase subunit e (ATP5I) in mediating the metabolic and antiproliferative effects of metformin in cancer cells.

Journal: eLife

Published: May 15, 2026

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics.

Mitochondrial ETF insufficiency drives neoplastic growth by selectively optimizing cancer bioenergetics.

Journal: eLife

Published: May 05, 2026

A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.

A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.

Journal: bioRxiv : the preprint server for biology

Published: February 09, 2026

CRISPR Screen Uncovers SLC26A2 as a Modulator of Tungsten Toxicity in Endochondral Ossification.

CRISPR Screen Uncovers SLC26A2 as a Modulator of Tungsten Toxicity in Endochondral Ossification.

Journal: Environmental research

Published: December 26, 2025

The scaffold protein PRR14L links the PP2A-TACC3 axis to mitotic fidelity and sensitivity to MPS1 inhibition.

The scaffold protein PRR14L links the PP2A-TACC3 axis to mitotic fidelity and sensitivity to MPS1 inhibition.

Journal: bioRxiv : the preprint server for biology

Published: November 24, 2025

CRISPR-based chemogenomic profiling reveals redox vulnerabilities to epigallocatechin-3-gallate and green tea polyphenol extract.

CRISPR-based chemogenomic profiling reveals redox vulnerabilities to epigallocatechin-3-gallate and green tea polyphenol extract.

Journal: Redox biology

Published: November 14, 2025

On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions.

On-target toxicity limits the efficacy of CDK11 inhibition against cancers with 1p36 deletions.

Journal: bioRxiv : the preprint server for biology

Published: August 06, 2025

CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity.

CDADC1 is a vertebrate-specific dCTP deaminase that metabolizes gemcitabine and decitabine to prevent cellular toxicity.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: June 12, 2025

Inhibiting the RNA helicase DDX3X in Burkitt lymphoma induces oxydative stress and impedes tumor progression in xenografts.

Inhibiting the RNA helicase DDX3X in Burkitt lymphoma induces oxydative stress and impedes tumor progression in xenografts.

Journal: Frontiers in cell and developmental biology

Published: June 05, 2025

Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations.

Genetic enhancers of partial PLK1 inhibition reveal hypersensitivity to kinetochore perturbations.

Journal: PLoS genetics

Published: April 05, 2023

Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition.

Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition.

Journal: Molecular cell

Published: September 15, 2022

Showing 1-12 of 27

Last Updated: 09/26/2026