Thomas A. Leonard

Vienna, Austria

Last Updated: 09/26/2026

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Found 24 publications

PHLPP is neither a Phosphatase nor a Tumor Suppressor.

PHLPP is neither a Phosphatase nor a Tumor Suppressor.

Journal: BioEssays : news and reviews in molecular, cellular and developmental biology

Published: April 07, 2026

PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor.

PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: April 01, 2025

A critical evaluation of protein kinase regulation by activation loop autophosphorylation.

A critical evaluation of protein kinase regulation by activation loop autophosphorylation.

Journal: eLife

Published: March 31, 2023

The membrane surface as a platform that organizes cellular and biochemical processes.

The membrane surface as a platform that organizes cellular and biochemical processes.

Journal: Developmental cell

Published: February 23, 2023

PKD autoinhibition in trans regulates activation loop autophosphorylation in cis.

PKD autoinhibition in trans regulates activation loop autophosphorylation in cis.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 06, 2023

ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1.

ATP-competitive and allosteric inhibitors induce differential conformational changes at the autoinhibitory interface of Akt1.

Journal: Structure (London, England : 1993)

Published: September 15, 2022

Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11.

Molecular basis for the recruitment of the Rab effector protein WDR44 by the GTPase Rab11.

Journal: The Journal of biological chemistry

Published: September 08, 2022

Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase.

Structure and regulation of the myotonic dystrophy kinase-related Cdc42-binding kinase.

Journal: Structure (London, England : 1993)

Published: March 24, 2022

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation.

Activation of the essential kinase PDK1 by phosphoinositide-driven trans-autophosphorylation.

Journal: Nature communications

Published: November 08, 2021

Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.

Structure of autoinhibited Akt1 reveals mechanism of PIP3-mediated activation.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: August 13, 2021

In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate.

In vitro reconstitution of Sgk3 activation by phosphatidylinositol 3-phosphate.

Journal: The Journal of biological chemistry

Published: April 16, 2021

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats.

Structures of three MORN repeat proteins and a re-evaluation of the proposed lipid-binding properties of MORN repeats.

Journal: PloS one

Published: July 30, 2020

Showing 1-12 of 24

Last Updated: 09/26/2026