Thomas A. Nicholson

Birmingham, ENG B152TT, United Kingdom

Last Updated: 09/26/2026

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Found 32 publications

REPROGRAM: REsilience PROmotion with GeRoprotectors: AssessMent of biological effect: Rationale and protocol for a trial of biological effect.

REPROGRAM: REsilience PROmotion with GeRoprotectors: AssessMent of biological effect: Rationale and protocol for a trial of biological effect.

Journal: PloS one
Published: May 01, 2026

mTOR signalling mediates the spinal osteoblast pathotype at the curve apex in adolescent idiopathic scoliosis.

mTOR signalling mediates the spinal osteoblast pathotype at the curve apex in adolescent idiopathic scoliosis.

Journal: Scientific reports
Published: February 18, 2026

Divergent roles of skeletal muscle 11β-HSD1 in age-related and chronic kidney disease-associated sarcopenia.

Divergent roles of skeletal muscle 11β-HSD1 in age-related and chronic kidney disease-associated sarcopenia.

Journal: European journal of endocrinology
Published: January 15, 2026

Increased quadriceps intermuscular adipose tissue in chronic liver disease is associated with an altered muscle transcriptome compared with healthy age matched controls.

Increased quadriceps intermuscular adipose tissue in chronic liver disease is associated with an altered muscle transcriptome compared with healthy age matched controls.

Journal: GeroScience
Published: October 03, 2025

Systemic Drivers and Molecular Mechanisms of Sarcopenia in Aetiology-Specific End-Stage Liver Disease.

Systemic Drivers and Molecular Mechanisms of Sarcopenia in Aetiology-Specific End-Stage Liver Disease.

Journal: Journal of cachexia, sarcopenia and muscle
Published: July 29, 2025

Obesity Reprogrammes Adipose Extracellular Vesicles to Induce Muscle Atrophy via miR-150-5p-Mediated Transcriptional Silencing.

Obesity Reprogrammes Adipose Extracellular Vesicles to Induce Muscle Atrophy via miR-150-5p-Mediated Transcriptional Silencing.

Journal: Journal of cachexia, sarcopenia and muscle
Published: June 20, 2025

From fat to flame: Multi-omic insights into how adipose-joint crosstalk stokes the fires of osteoarthritis.

From fat to flame: Multi-omic insights into how adipose-joint crosstalk stokes the fires of osteoarthritis.

Journal: Osteoarthritis and cartilage
Published: April 08, 2025

PEPITEM Regulates the Synovial Microenvironment During Immune-Mediated Inflammatory Arthritis to Limit Disease.

PEPITEM Regulates the Synovial Microenvironment During Immune-Mediated Inflammatory Arthritis to Limit Disease.

Journal: Arthritis & rheumatology (Hoboken, N.J.)
Published: March 19, 2025

Major Traumatic Injury and Exposure to Mitochondrial-Derived Damage-Associated Molecular Patterns Promotes Neutrophil Survival Accompanied by Stabilisation of the Anti-Apoptotic Protein Mcl-1.

Major Traumatic Injury and Exposure to Mitochondrial-Derived Damage-Associated Molecular Patterns Promotes Neutrophil Survival Accompanied by Stabilisation of the Anti-Apoptotic Protein Mcl-1.

Journal: Cells
Published: March 18, 2025

Accelerated epigenetic ageing after burn injury.

Accelerated epigenetic ageing after burn injury.

Journal: GeroScience
Published: October 22, 2024

A detailed methodology for a three-dimensional, self-structuring bone model that supports the differentiation of osteoblasts towards osteocytes and the production of a complex collagen-rich mineralised matrix.

A detailed methodology for a three-dimensional, self-structuring bone model that supports the differentiation of osteoblasts towards osteocytes and the production of a complex collagen-rich mineralised matrix.

Journal: F1000Research
Published: May 23, 2024

Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppression.

Severe thermal and major traumatic injury results in elevated plasma concentrations of total heme that are associated with poor clinical outcomes and systemic immune suppression.

Journal: Frontiers in immunology
Published: April 13, 2024
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Last Updated: 09/26/2026