Thomas Calzascia

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 20 publications

Defining immune reset: achieving sustained remission in autoimmune diseases.

Defining immune reset: achieving sustained remission in autoimmune diseases.

Journal: Nature reviews. Immunology

Published: January 23, 2025

Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants.

Nonhematopoietic IRAK1 drives arthritis via neutrophil chemoattractants.

Journal: JCI insight

Published: March 22, 2021

CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo.

CARD10 cleavage by MALT1 restricts lung carcinoma growth in vivo.

Journal: Oncogenesis

Published: December 11, 2020

Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood.

Optimization of the In Vivo Potency of Pyrazolopyrimidine MALT1 Protease Inhibitors by Reducing Metabolism and Increasing Potency in Whole Blood.

Journal: Journal of medicinal chemistry

Published: November 20, 2020

Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology.

Pharmacological Inhibition of MALT1 Protease Leads to a Progressive IPEX-Like Pathology.

Journal: Frontiers in immunology

Published: January 17, 2020

Requirement of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor-Induced Arthritis, but Not Fcγ Receptor-Mediated Platelet Elimination, in Mice.

Requirement of Mucosa-Associated Lymphoid Tissue Lymphoma Translocation Protein 1 Protease Activity for Fcγ Receptor-Induced Arthritis, but Not Fcγ Receptor-Mediated Platelet Elimination, in Mice.

Journal: Arthritis & rheumatology (Hoboken, N.J.)

Published: October 20, 2019

Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity.

Malt1 Protease Deficiency in Mice Disrupts Immune Homeostasis at Environmental Barriers and Drives Systemic T Cell-Mediated Autoimmunity.

Journal: Journal of immunology (Baltimore, Md. : 1950)

Published: March 19, 2019

Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies.

Development of Anti-CD32b Antibodies with Enhanced Fc Function for the Treatment of B and Plasma Cell Malignancies.

Journal: Molecular cancer therapeutics

Published: January 24, 2019

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity.

Myeloid Innate Signaling Pathway Regulation by MALT1 Paracaspase Activity.

Journal: Journal of visualized experiments : JoVE

Published: January 22, 2019

Selective MALT1 paracaspase inhibition does not block TNF-α production downstream of TLR4 in myeloid cells.

Selective MALT1 paracaspase inhibition does not block TNF-α production downstream of TLR4 in myeloid cells.

Journal: Immunology letters

Published: October 20, 2017

The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition.

The T-cell fingerprint of MALT1 paracaspase revealed by selective inhibition.

Journal: Immunology and cell biology

Published: May 16, 2017

Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.

Two Antagonistic MALT1 Auto-Cleavage Mechanisms Reveal a Role for TRAF6 to Unleash MALT1 Activation.

Journal: PloS one

Published: July 01, 2016

Showing 1-12 of 20

Last Updated: 09/26/2026