Thomas D. Meek

Neurosurgery

511 N Alleghaney Ave
Odessa, TX 79761

Last Updated: 09/26/2026

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Found 30 publications

Substrate Specificity and Kinetic Mechanism of the NAD+-Dependent Deacylase from Mycobacterium tuberculosis, Rv1151c (Mt-Sirt).

Substrate Specificity and Kinetic Mechanism of the NAD+-Dependent Deacylase from Mycobacterium tuberculosis, Rv1151c (Mt-Sirt).

Journal: Biochemistry

Published: July 13, 2026

Peptidomimetic α,β-Unsaturated Ethyl Esters Are Irreversible Inactivators of Human Cathepsin L and Are Potent Inhibitors of SARS-CoV-2 in Cellular Models of COVID-19.

Peptidomimetic α,β-Unsaturated Ethyl Esters Are Irreversible Inactivators of Human Cathepsin L and Are Potent Inhibitors of SARS-CoV-2 in Cellular Models of COVID-19.

Journal: Journal of medicinal chemistry

Published: April 21, 2026

Author Correction: SERRATE drives phase separation behaviours to regulate m6A modification and miRNA biogenesis.

Author Correction: SERRATE drives phase separation behaviours to regulate m6A modification and miRNA biogenesis.

Journal: Nature cell biology

Published: February 09, 2026

Reciprocal regulation of m 6 A modification and miRNA production machineries via phase separation-dependent and -independent mechanisms.

Reciprocal regulation of m 6 A modification and miRNA production machineries via phase separation-dependent and -independent mechanisms.

Journal: bioRxiv : the preprint server for biology

Published: September 11, 2024

Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics.

Catalytic Mechanism of SARS-CoV-2 3-Chymotrypsin-Like Protease as Determined by Steady-State and Pre-Steady-State Kinetics.

Journal: ACS catalysis

Published: August 28, 2024

SERRATE drives phase separation behaviours to regulate m6A modification and miRNA biogenesis.

SERRATE drives phase separation behaviours to regulate m6A modification and miRNA biogenesis.

Journal: Nature cell biology

Published: December 07, 2023

Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors.

Kinetic and Structural Characterization of Trypanosoma cruzi Hypoxanthine-Guanine-Xanthine Phosphoribosyltransferases and Repurposing of Transition-State Analogue Inhibitors.

Journal: Biochemistry

Published: July 07, 2023

Kinetic Characterization and Inhibition of Trypanosoma cruzi Hypoxanthine-Guanine Phosphoribosyltransferases.

Kinetic Characterization and Inhibition of Trypanosoma cruzi Hypoxanthine-Guanine Phosphoribosyltransferases.

Journal: Biochemistry

Published: October 04, 2022

The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues.

The design of protozoan phosphoribosyltransferase inhibitors containing non-charged phosphate mimic residues.

Journal: Bioorganic & medicinal chemistry

Published: August 18, 2022

Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents.

Self-Masked Aldehyde Inhibitors of Human Cathepsin L Are Potent Anti-CoV-2 Agents.

Journal: Frontiers in chemistry

Published: February 01, 2022

Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.

Potent Anti-SARS-CoV-2 Activity by the Natural Product Gallinamide A and Analogues via Inhibition of Cathepsin L.

Journal: Journal of medicinal chemistry

Published: November 03, 2021

Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active.

Characterization of adenine phosphoribosyltransferase (APRT) activity in Trypanosoma brucei brucei: Only one of the two isoforms is kinetically active.

Journal: PLoS neglected tropical diseases

Published: October 19, 2021

Showing 1-12 of 30

Last Updated: 09/26/2026