Thomas Duflot

Rouen, France

Last Updated: 09/26/2026

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Found 50 publications

Fragment-Based Discovery of Fenamic Acids as Pan-Species Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.

Fragment-Based Discovery of Fenamic Acids as Pan-Species Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain.

Journal: ACS chemical biology

Published: May 25, 2026

Early bictegravir failure and emergence of R263K-mediated class-wide HIV integrase inhibitors resistance linked to over-the-counter supplement use.

Early bictegravir failure and emergence of R263K-mediated class-wide HIV integrase inhibitors resistance linked to over-the-counter supplement use.

Journal: The Journal of antimicrobial chemotherapy

Published: May 19, 2026

Linezolid use in postoperative central nervous system infections: a pharmacokinetic simulation-based approach for critically ill patients.

Linezolid use in postoperative central nervous system infections: a pharmacokinetic simulation-based approach for critically ill patients.

Journal: Anaesthesia, critical care & pain medicine

Published: September 19, 2025

AEROfen: protocol for a phase I, open-label, randomised crossover study evaluating the efficiency of nebulised fentanyl in healthy volunteers - comparing facial versus intranasal administration via pharmacometric modelling.

AEROfen: protocol for a phase I, open-label, randomised crossover study evaluating the efficiency of nebulised fentanyl in healthy volunteers - comparing facial versus intranasal administration via pharmacometric modelling.

Journal: BMJ open

Published: July 04, 2025

The phosphatase activity of soluble epoxide hydrolase regulates vascular calcification through the metabolism of pyrophosphate anions.

The phosphatase activity of soluble epoxide hydrolase regulates vascular calcification through the metabolism of pyrophosphate anions.

Journal: Cell death & disease

Published: April 25, 2025

Dynamic functional luminal imaging probe analysis of the anal sphincter opening function during straining in healthy volunteers.

Dynamic functional luminal imaging probe analysis of the anal sphincter opening function during straining in healthy volunteers.

Journal: American journal of physiology. Gastrointestinal and liver physiology

Published: April 08, 2025

Population pharmacokinetics of cefazolin in neurosurgical antibiotic prophylaxis.

Population pharmacokinetics of cefazolin in neurosurgical antibiotic prophylaxis.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: March 20, 2025

Effect of Alternative Administrations on P2Y12 Receptor Inhibitors' Pharmacokinetics and Pharmacodynamics: Systematic Review and Meta-Analysis.

Effect of Alternative Administrations on P2Y12 Receptor Inhibitors' Pharmacokinetics and Pharmacodynamics: Systematic Review and Meta-Analysis.

Journal: The AAPS journal

Published: January 08, 2025

Assessing the Impact of Multiple Imputation Algorithms on Pharmacokinetic Model Performance: A Simulation-Based Study.

Assessing the Impact of Multiple Imputation Algorithms on Pharmacokinetic Model Performance: A Simulation-Based Study.

Journal: The AAPS journal

Published: January 07, 2025

Plasma metabolomics signatures predict COVID-19 patient outcome at ICU admission comparable to clinical scores.

Plasma metabolomics signatures predict COVID-19 patient outcome at ICU admission comparable to clinical scores.

Journal: Scientific reports

Published: November 18, 2024

Unraveling Ceftriaxone Dosing: Free Drug Prediction, Threshold Optimization, and Model Validation.

Unraveling Ceftriaxone Dosing: Free Drug Prediction, Threshold Optimization, and Model Validation.

Journal: The AAPS journal

Published: November 18, 2024

Chronic endothelial dopamine receptor stimulation improves endothelial function and hemodynamics in autosomal dominant polycystic kidney disease.

Chronic endothelial dopamine receptor stimulation improves endothelial function and hemodynamics in autosomal dominant polycystic kidney disease.

Journal: Kidney international

Published: September 29, 2023

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Last Updated: 09/26/2026