Thomas Goiran

Valbonne, 06560, France

Last Updated: 09/26/2026

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Found 10 publications

α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistance.

α-synuclein expression in glioblastoma restores tumor suppressor function and rescues temozolomide drug resistance.

Journal: Cell death & disease
Published: July 29, 2024

The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons.

The Parkinson's disease risk gene cathepsin B promotes fibrillar alpha-synuclein clearance, lysosomal function and glucocerebrosidase activity in dopaminergic neurons.

Journal: Research square
Published: April 02, 2024

Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.

Transcription- and phosphorylation-dependent control of a functional interplay between XBP1s and PINK1 governs mitophagy and potentially impacts Parkinson disease pathophysiology.

Journal: Autophagy
Published: May 25, 2021

Nuclear TP53: An unraveled function as transcriptional repressor of PINK1.

Nuclear TP53: An unraveled function as transcriptional repressor of PINK1.

Journal: Autophagy
Published: May 12, 2018

Presenilins at the crossroad of a functional interplay between PARK2/PARKIN and PINK1 to control mitophagy: Implication for neurodegenerative diseases.

Presenilins at the crossroad of a functional interplay between PARK2/PARKIN and PINK1 to control mitophagy: Implication for neurodegenerative diseases.

Journal: Autophagy
Published: September 16, 2017

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation.

Nuclear p53-mediated repression of autophagy involves PINK1 transcriptional down-regulation.

Journal: Cell death and differentiation
Published: February 13, 2017

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.

β-Amyloid Precursor Protein Intracellular Domain Controls Mitochondrial Function by Modulating Phosphatase and Tensin Homolog-Induced Kinase 1 Transcription in Cells and in Alzheimer Mice Models.

Journal: Biological psychiatry
Published: August 26, 2016

Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells.

Metformin-induced energy deficiency leads to the inhibition of lipogenesis in prostate cancer cells.

Journal: Oncotarget
Published: February 16, 2015

Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.

Parkin differently regulates presenilin-1 and presenilin-2 functions by direct control of their promoter transcription.

Journal: Journal of molecular cell biology
Published: January 30, 2013

Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity.

Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity.

Journal: Oncogene
Published: July 18, 2012
Showing 1-10 of 10

Last Updated: 09/26/2026