Thomas H. Sharp

Leiden, ZH, Netherlands

Last Updated: 09/26/2026

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Found 46 publications

Dual-colour super-resolution cryoCLEM in mammalian cells using the fluorescent proteins rsTagRFP and rsEGFP2.

Dual-colour super-resolution cryoCLEM in mammalian cells using the fluorescent proteins rsTagRFP and rsEGFP2.

Journal: Journal of structural biology

Published: July 09, 2025

Nuclear Protein Aggregates Disrupt RNA Processing and Alter Biomechanics in a Muscle Cell Model of OPMD.

Nuclear Protein Aggregates Disrupt RNA Processing and Alter Biomechanics in a Muscle Cell Model of OPMD.

Journal: Aging and disease

Published: June 02, 2025

Modulation of immunoglobulin G oligomerization by variable domain glycans: A mechanism to regulate complement activation.

Modulation of immunoglobulin G oligomerization by variable domain glycans: A mechanism to regulate complement activation.

Journal: PNAS nexus

Published: May 02, 2025

Inducing Cancer Cell Killing Using DNA Nanostructure-Mediated Superclustering of Death Receptors.

Inducing Cancer Cell Killing Using DNA Nanostructure-Mediated Superclustering of Death Receptors.

Journal: Nano letters

Published: April 08, 2025

Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding.

Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding.

Journal: Communications biology

Published: March 27, 2025

Streamlining segmentation of cryo-electron tomography datasets with Ais.

Streamlining segmentation of cryo-electron tomography datasets with Ais.

Journal: eLife

Published: December 20, 2024

Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein.

Structural basis for surface activation of the classical complement cascade by the short pentraxin C-reactive protein.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: September 06, 2024

Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors.

Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors.

Journal: Molecular cell

Published: July 01, 2024

Design and Synthesis of DNA Origami Nanostructures to Control TNF Receptor Activation.

Design and Synthesis of DNA Origami Nanostructures to Control TNF Receptor Activation.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: May 06, 2024

Imaging intracellular components in situ using super-resolution cryo-correlative light and electron microscopy.

Imaging intracellular components in situ using super-resolution cryo-correlative light and electron microscopy.

Journal: Methods in cell biology

Published: May 05, 2024

Building a super-resolution fluorescence cryomicroscope.

Building a super-resolution fluorescence cryomicroscope.

Journal: Methods in cell biology

Published: May 05, 2024

Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system.

Selection and characterization of a peptide-based complement modulator targeting C1 of the innate immune system.

Journal: RSC chemical biology

Published: April 09, 2024

Showing 1-12 of 46

Last Updated: 09/26/2026