Thomas H. Sisson

Thomas H. Sisson

Pulmonary Medicine | Intensive Care Medicine
1500 E Medical Center Dr
Floor 3 Reception C
Ann Arbor, MI 48109

Last Updated: 09/26/2026

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Found 32 publications

Targeting Plasminogen Activator Inhibitor-1 with a Novel Small Molecule Inhibitor Attenuates Lung Fibrosis.

Targeting Plasminogen Activator Inhibitor-1 with a Novel Small Molecule Inhibitor Attenuates Lung Fibrosis.

Journal: Research square
Published: September 02, 2025

A potent inhibitor of PAI-1, MDI-2517, mitigates disease severity in a preclinical systemic sclerosis model.

A potent inhibitor of PAI-1, MDI-2517, mitigates disease severity in a preclinical systemic sclerosis model.

Journal: JCI insight
Published: April 29, 2025

PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis.

PAI-1 Interaction with Sortilin Related Receptor-1 is Required for Lung Fibrosis.

Journal: bioRxiv : the preprint server for biology
Published: August 30, 2024

PAI-1 interaction with sortilin-related receptor 1 is required for lung fibrosis.

PAI-1 interaction with sortilin-related receptor 1 is required for lung fibrosis.

Journal: JCI insight
Published: August 20, 2024

SORL1 is a receptor for tau that promotes tau seeding.

SORL1 is a receptor for tau that promotes tau seeding.

Journal: The Journal of biological chemistry
Published: January 05, 2024

CD36/Lyn kinase interactions within macrophages promotes pulmonary fibrosis in response to oxidized phospholipid.

CD36/Lyn kinase interactions within macrophages promotes pulmonary fibrosis in response to oxidized phospholipid.

Journal: Respiratory research
Published: May 17, 2023

Defibrotide Therapy for SARS-CoV-2 ARDS.

Defibrotide Therapy for SARS-CoV-2 ARDS.

Journal: Chest
Published: January 28, 2022

Sustained Club Cell Injury in Mice Induces Histopathologic Features of Deployment-Related Constrictive Bronchiolitis.

Sustained Club Cell Injury in Mice Induces Histopathologic Features of Deployment-Related Constrictive Bronchiolitis.

Journal: The American journal of pathology
Published: April 29, 2021

Diverse Injury Pathways Induce Alveolar Epithelial Cell CCL2/12, Which Promotes Lung Fibrosis.

Diverse Injury Pathways Induce Alveolar Epithelial Cell CCL2/12, Which Promotes Lung Fibrosis.

Journal: American journal of respiratory cell and molecular biology
Published: January 11, 2020

Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis.

Urokinase Plasminogen Activator Overexpression Reverses Established Lung Fibrosis.

Journal: Thrombosis and haemostasis
Published: November 10, 2019

Phosphodiesterase 4 inhibition reduces lung fibrosis following targeted type II alveolar epithelial cell injury.

Phosphodiesterase 4 inhibition reduces lung fibrosis following targeted type II alveolar epithelial cell injury.

Journal: Physiological reports
Published: April 02, 2018

Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli.

Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli.

Journal: Respiratory research
Published: March 08, 2018
Showing 1-12 of 32

Last Updated: 09/26/2026