Thomas L. Lau

Internal Medicine

1221 Kapiolani Blvd Ste 515
Honolulu, HI 96814

Last Updated: 09/26/2026

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Found 1 publications

Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: structure-activity relationships, lead optimization, and chronic in vivo efficacy.

Discovery of trifluoromethyl(pyrimidin-2-yl)azetidine-2-carboxamides as potent, orally bioavailable TGR5 (GPBAR1) agonists: structure-activity relationships, lead optimization, and chronic in vivo efficacy.

Journal: Journal of medicinal chemistry

Published: March 27, 2014

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Last Updated: 09/26/2026