Thomas L. Williams
Cambridge, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 19 publications
International Union of Basic and Clinical Pharmacology. CXXI. Apelin receptor pharmacology in the human cardiovascular system and emerging clinical applications.
Journal: Pharmacological reviews
Published: August 08, 2025
Localization of the therapeutic targets for endothelin receptor antagonists and sodium-glucose co-transporter 2 inhibitors in the chronic liver disease, primary sclerosing cholangitis.
Journal: Frontiers in pharmacology
Published: August 06, 2025
Microarray analysis demonstrates up-regulation of the endothelin-1 gene with compensatory down-regulation of the ETA receptor gene in human portal vein.
Journal: Bioscience reports
Published: May 13, 2024
Co-localization of the sodium-glucose co-transporter-2 channel (SGLT-2) with endothelin ETA and ETB receptors in human cardiorenal tissue.
Journal: Bioscience reports
Published: May 08, 2024
Structural and functional determination of peptide versus small molecule ligand binding at the apelin receptor.
Journal: Nature communications
Published: February 19, 2024
Expression of the apelin receptor, a novel potential therapeutic target, and its endogenous ligands in diverse stem cell populations in human glioblastoma.
Journal: Frontiers in neuroscience
Published: January 31, 2024
The biased apelin receptor agonist, MM07, reverses Sugen/hypoxia-induced pulmonary arterial hypertension as effectively as the endothelin antagonist macitentan.
Journal: Frontiers in pharmacology
Published: January 12, 2024
Current and future strategies for targeting the endothelin pathway in cardiovascular disease.
Journal: Nature cardiovascular research
Published: April 05, 2023
Expanding the apelin receptor pharmacological toolbox using novel fluorescent ligands.
Journal: Frontiers in endocrinology
Published: January 06, 2023
Apelin is expressed throughout the human kidney, is elevated in chronic kidney disease & associates independently with decline in kidney function.
Journal: British journal of clinical pharmacology
Published: May 05, 2022
Inducible apelin receptor knockdown reduces differentiation efficiency and contractility of hESC-derived cardiomyocytes.
Journal: Cardiovascular research
Published: December 17, 2021
Differential expression in humans of the viral entry receptor ACE2 compared with the short deltaACE2 isoform lacking SARS-CoV-2 binding sites.
Journal: Scientific reports
Published: September 24, 2021
Last Updated: 09/26/2026