Thomas M. Leissing
Oxford, ENG OX37DQ, United Kingdom
Last Updated: 09/26/2026
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Found 13 publications
Deficiency of factor-inhibiting HIF creates a tumor-promoting immune microenvironment.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: February 29, 2024
Biochemical and Structural Insights into FIH-Catalysed Hydroxylation of Transient Receptor Potential Ankyrin Repeat Domains.
Journal: Chembiochem : a European journal of chemical biology
Published: October 06, 2022
Factor inhibiting HIF can catalyze two asparaginyl hydroxylations in VNVN motifs of ankyrin fold proteins.
Journal: The Journal of biological chemistry
Published: November 02, 2021
X-ray free-electron laser studies reveal correlated motion during isopenicillin N synthase catalysis.
Journal: Science advances
Published: February 10, 2021
Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.
Journal: Nature chemistry
Published: December 12, 2020
Structural Investigations of the Inhibition of Escherichia coli AmpC β-Lactamase by Diazabicyclooctanes.
Journal: Antimicrobial agents and chemotherapy
Published: October 06, 2020
Bicyclic Boronates as Potent Inhibitors of AmpC, the Class C β-Lactamase from Escherichia coli.
Journal: Biomolecules
Published: April 30, 2020
CagA-ASPP2 complex mediates loss of cell polarity and favors H. pylori colonization of human gastric organoids.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: January 23, 2020
A human protein hydroxylase that accepts D-residues.
Journal: Communications chemistry
Published: October 14, 2019
Molecular and cellular mechanisms of HIF prolyl hydroxylase inhibitors in clinical trials.
Journal: Chemical science
Published: May 10, 2017
Last Updated: 09/26/2026