Thomas M. Durcan

Montreal, QC, Canada

Last Updated: 09/26/2026

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Found 123 publications

BetaII-spectrin gaps and patches emerge from the patterned assembly of the actin/spectrin membrane skeleton in human motor neuron axons.

BetaII-spectrin gaps and patches emerge from the patterned assembly of the actin/spectrin membrane skeleton in human motor neuron axons.

Journal: eLife

Published: September 08, 2026

A Human Vocal Fold Organ-On-Chip for Studying Platform-Dependent Mucosal Responses to Particulate Matter.

A Human Vocal Fold Organ-On-Chip for Studying Platform-Dependent Mucosal Responses to Particulate Matter.

Journal: bioRxiv : the preprint server for biology

Published: June 12, 2026

Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonism.

Neural cell state modulation by PARK2 and dopaminergic neuroprotection by small molecule Parkin agonism.

Journal: bioRxiv : the preprint server for biology

Published: April 10, 2026

Stress-Adaptive Biomaterials With Tunable Yielding Architectures Regulate Organoid Morphogenesis.

Stress-Adaptive Biomaterials With Tunable Yielding Architectures Regulate Organoid Morphogenesis.

Journal: Small (Weinheim an der Bergstrasse, Germany)

Published: April 06, 2026

N-terminal acetylation reduces synuclein pathology in models of Parkinson's disease.

N-terminal acetylation reduces synuclein pathology in models of Parkinson's disease.

Journal: Neurobiology of disease

Published: March 29, 2026

An automated workflow for quantifying the formation of synuclein aggregates in human dopaminergic neurons.

An automated workflow for quantifying the formation of synuclein aggregates in human dopaminergic neurons.

Journal: Methods (San Diego, Calif.)

Published: February 06, 2026

A high-content imaging workflow to screen for molecules that reduce cellular uptake of α-synuclein preformed fibrils.

A high-content imaging workflow to screen for molecules that reduce cellular uptake of α-synuclein preformed fibrils.

Journal: Methods (San Diego, Calif.)

Published: February 06, 2026

A Streamlined Workflow for Purkinje Cell Labeling and High-Resolution Analyses of Dendrites and Spines in Mice.

A Streamlined Workflow for Purkinje Cell Labeling and High-Resolution Analyses of Dendrites and Spines in Mice.

Journal: eNeuro

Published: December 09, 2025

Single nuclear RNA sequencing shows altered microglial and astrocytic functions in post-mortem Parkinson's disease tissue.

Single nuclear RNA sequencing shows altered microglial and astrocytic functions in post-mortem Parkinson's disease tissue.

Journal: BMC genomic data

Published: December 04, 2025

STIP1/HOP promotes the formation of cytotoxic α-synuclein oligomers.

STIP1/HOP promotes the formation of cytotoxic α-synuclein oligomers.

Journal: Molecular neurodegeneration advances

Published: November 14, 2025

LRRK2 kinase mediates increased GCase activity in microglia in response to IFNγ-induced proinflammatory stimulation.

LRRK2 kinase mediates increased GCase activity in microglia in response to IFNγ-induced proinflammatory stimulation.

Journal: NPJ Parkinson's disease

Published: October 10, 2025

A guide to selecting high-performing antibodies for Heterogeneous nuclear ribonucleoproteins A2/B1(hnRNP A2/B1) (UniProt ID: P22626) for use in western blot, immunoprecipitation, and immunofluorescence.

A guide to selecting high-performing antibodies for Heterogeneous nuclear ribonucleoproteins A2/B1(hnRNP A2/B1) (UniProt ID: P22626) for use in western blot, immunoprecipitation, and immunofluorescence.

Journal: F1000Research

Published: September 30, 2025

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Last Updated: 09/26/2026