Thomas Pournatzis-Gonatopoulos

Toronto, ON M5S3E1, Canada

Last Updated: 09/26/2026

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Found 24 publications

Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration.

Intron Retention Controls Localization of lncRNAs PURPL and MALAT1 to Promote Cell Proliferation and Migration.

Journal: bioRxiv : the preprint server for biology
Published: February 27, 2026

RBM39 modulates UPR signaling through alternative splicing of IRE1α/ERN1.

RBM39 modulates UPR signaling through alternative splicing of IRE1α/ERN1.

Journal: Genes & development
Published: January 06, 2026

Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics.

Single-cell exon deletion profiling reveals splicing events that shape gene expression and cell state dynamics.

Journal: Nature communications
Published: November 20, 2025

RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria.

RNA-coupled CRISPR Screens Reveal ZNF207 as a Regulator of LMNA Aberrant Splicing in Progeria.

Journal: bioRxiv : the preprint server for biology
Published: June 26, 2025

RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria.

RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria.

Journal: Molecular cell
Published: February 11, 2025

Genome-scale exon perturbation screens uncover exons critical for cell fitness.

Genome-scale exon perturbation screens uncover exons critical for cell fitness.

Journal: Molecular cell
Published: October 01, 2023

Proteomic study identifies Aurora-A-mediated regulation of alternative splicing through multiple splicing factors.

Proteomic study identifies Aurora-A-mediated regulation of alternative splicing through multiple splicing factors.

Journal: The Journal of biological chemistry
Published: September 28, 2023

Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.

Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis.

Journal: Molecular cell
Published: November 10, 2021

Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening.

Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening.

Journal: Nature protocols
Published: November 28, 2020

Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline.

Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline.

Journal: Nature protocols
Published: August 26, 2020

Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder.

Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder.

Journal: Current opinion in genetics & development
Published: March 25, 2020

Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions.

Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
Published: June 24, 2019
Showing 1-12 of 24

Last Updated: 09/26/2026