Thomas R. Kleyman

Thomas R. Kleyman

Nephrology
200 Lothrop Street, A915 Scaife Hall, UPMC Presbyterian Hospital
Pittsburgh, PA 15213

Last Updated: 09/26/2026

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Found 124 publications

Abnormal activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron contributes to fructose-induced salt-sensitive hypertension.

Abnormal activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron contributes to fructose-induced salt-sensitive hypertension.

Journal: American journal of physiology. Renal physiology
Published: July 11, 2026

Abnormal activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron contributes to fructose-induced salt-sensitive hypertension.

Abnormal activation of the mineralocorticoid receptor in the aldosterone-sensitive distal nephron contributes to fructose-induced salt-sensitive hypertension.

Journal: American journal of physiology. Renal physiology
Published: July 11, 2026

A sodium-HIF1α axis coordinates immune metabolic reprogramming and mitochondrial remodeling in salt-sensitive hypertension.

A sodium-HIF1α axis coordinates immune metabolic reprogramming and mitochondrial remodeling in salt-sensitive hypertension.

Journal: Research square
Published: May 04, 2026

A sodium-HIF1α axis coordinates immune metabolic reprogramming and mitochondrial remodeling in salt-sensitive hypertension.

A sodium-HIF1α axis coordinates immune metabolic reprogramming and mitochondrial remodeling in salt-sensitive hypertension.

Journal: Research square
Published: May 04, 2026

Contribution of murine strain background to Na+ reabsorption in the kidney.

Contribution of murine strain background to Na+ reabsorption in the kidney.

Journal: bioRxiv : the preprint server for biology
Published: March 27, 2026

Smooth Muscle βENaC Deletion Induces Moderate Hypertension and Renal Injury.

Smooth Muscle βENaC Deletion Induces Moderate Hypertension and Renal Injury.

Journal: Kidney360
Published: March 16, 2026

Acid-sensing ion channel 2a assembles with epithelial Na+ channel β and γ subunits to form mechanosensitive ion channels.

Acid-sensing ion channel 2a assembles with epithelial Na+ channel β and γ subunits to form mechanosensitive ion channels.

Journal: The Journal of biological chemistry
Published: January 27, 2026

Resistance to doxorubicin-induced proteinuria and proteolytic activation of ENaC in 129S2/SvPas mice.

Resistance to doxorubicin-induced proteinuria and proteolytic activation of ENaC in 129S2/SvPas mice.

Journal: Physiological reports
Published: July 11, 2025

The scaffold protein IQGAP1 regulates the epithelial Na+ channel.

The scaffold protein IQGAP1 regulates the epithelial Na+ channel.

Journal: The Journal of biological chemistry
Published: June 16, 2025

Canagliflozin Inhibits Electrogenic Na+ Transport in Mouse Cortical Collecting Duct Cells.

Canagliflozin Inhibits Electrogenic Na+ Transport in Mouse Cortical Collecting Duct Cells.

Journal: Function (Oxford, England)
Published: June 11, 2025

Effect of sex chromosome complement versus gonadal hormones on abundance of renal transporters.

Effect of sex chromosome complement versus gonadal hormones on abundance of renal transporters.

Journal: American journal of physiology. Renal physiology
Published: March 10, 2025

Paraoxonase 3 regulates the pore-forming α subunit of the large-conductance K+ channel.

Paraoxonase 3 regulates the pore-forming α subunit of the large-conductance K+ channel.

Journal: Biochimica et biophysica acta. Molecular cell research
Published: February 04, 2025
Showing 1-12 of 124

Last Updated: 09/26/2026