Thomas Spath-Muller

Zurich, ZH, Switzerland

Last Updated: 09/26/2026

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Found 23 publications

Enrichment of Full AAV2 Using Multicolumn Countercurrent Solvent Gradient Purification (MCSGP).

Enrichment of Full AAV2 Using Multicolumn Countercurrent Solvent Gradient Purification (MCSGP).

Journal: Biotechnology and bioengineering

Published: February 15, 2025

Integrated multidimensional chromatography on preparative scale for oligonucleotides purification.

Integrated multidimensional chromatography on preparative scale for oligonucleotides purification.

Journal: Journal of chromatography. A

Published: July 30, 2024

UV-based dynamic control improves the robustness of multicolumn countercurrent solvent gradient purification of oligonucleotides.

UV-based dynamic control improves the robustness of multicolumn countercurrent solvent gradient purification of oligonucleotides.

Journal: Biotechnology journal

Published: March 16, 2024

Continuous Countercurrent Chromatography in Protein Purification.

Continuous Countercurrent Chromatography in Protein Purification.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: August 30, 2023

Enrichment and recovery of oligonucleotide impurities by N-Rich twin-column continuous chromatography.

Enrichment and recovery of oligonucleotide impurities by N-Rich twin-column continuous chromatography.

Journal: Journal of chromatography. B, Analytical technologies in the biomedical and life sciences

Published: May 10, 2022

Enrichment and purification of peptide impurities using twin-column continuous chromatography.

Enrichment and purification of peptide impurities using twin-column continuous chromatography.

Journal: Journal of chromatography. A

Published: December 30, 2021

Continuous countercurrent chromatographic twin-column purification of oligonucleotides: The role of the displacement effect.

Continuous countercurrent chromatographic twin-column purification of oligonucleotides: The role of the displacement effect.

Journal: Biotechnology and bioengineering

Published: November 24, 2021

Purification of a GalNAc-cluster-conjugated oligonucleotide by reversed-phase twin-column continuous chromatography.

Purification of a GalNAc-cluster-conjugated oligonucleotide by reversed-phase twin-column continuous chromatography.

Journal: Journal of chromatography. A

Published: October 18, 2021

Continued insights into virus clearance validation across continuous capture chromatography.

Continued insights into virus clearance validation across continuous capture chromatography.

Journal: Biotechnology and bioengineering

Published: October 06, 2020

Oligonucleotides: Current Trends and Innovative Applications in the Synthesis, Characterization, and Purification.

Oligonucleotides: Current Trends and Innovative Applications in the Synthesis, Characterization, and Purification.

Journal: Biotechnology journal

Published: January 22, 2020

Design space and robustness analysis of batch and counter-current frontal chromatography processes for the removal of antibody aggregates.

Design space and robustness analysis of batch and counter-current frontal chromatography processes for the removal of antibody aggregates.

Journal: Journal of chromatography. A

Published: November 11, 2019

Virus clearance validation across continuous capture chromatography.

Virus clearance validation across continuous capture chromatography.

Journal: Biotechnology and bioengineering

Published: February 07, 2019

Showing 1-12 of 23

Last Updated: 09/26/2026