Thorsten Fritzius

Basel, BS 4056, Switzerland

Last Updated: 09/26/2026

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Found 18 publications

Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety.

Binding of HCN channels to GABAB receptors in dopamine neurons of the VTA limits synaptic inhibition and prevents the development of anxiety.

Journal: Neurobiology of disease
Published: October 08, 2024

Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release.

Monoallelic de novo AJAP1 loss-of-function variants disrupt trans-synaptic control of neurotransmitter release.

Journal: Science advances
Published: July 10, 2024

Preassembly of specific Gβγ subunits at GABAB receptors through auxiliary KCTD proteins accelerates channel gating.

Preassembly of specific Gβγ subunits at GABAB receptors through auxiliary KCTD proteins accelerates channel gating.

Journal: Biochemical pharmacology
Published: January 19, 2024

Synaptotagmin-11 facilitates assembly of a presynaptic signaling complex in post-Golgi cargo vesicles.

Synaptotagmin-11 facilitates assembly of a presynaptic signaling complex in post-Golgi cargo vesicles.

Journal: EMBO reports
Published: August 18, 2023

Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity.

Soluble amyloid-β precursor peptide does not regulate GABAB receptor activity.

Journal: eLife
Published: July 21, 2022

GABAB receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals.

GABAB receptor auxiliary subunits modulate Cav2.3-mediated release from medial habenula terminals.

Journal: eLife
Published: March 10, 2021

Structural Basis of GABAB Receptor Regulation and Signaling.

Structural Basis of GABAB Receptor Regulation and Signaling.

Journal: Current topics in behavioral neurosciences
Published: August 20, 2020

Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.

Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.

Journal: Neuropharmacology
Published: April 17, 2020

Targeting the γ-Aminobutyric Acid Type B (GABAB) Receptor Complex: Development of Inhibitors Targeting the K+ Channel Tetramerization Domain (KCTD) Containing Proteins/GABAB Receptor Protein-Protein Interaction.

Targeting the γ-Aminobutyric Acid Type B (GABAB) Receptor Complex: Development of Inhibitors Targeting the K+ Channel Tetramerization Domain (KCTD) Containing Proteins/GABAB Receptor Protein-Protein Interaction.

Journal: Journal of medicinal chemistry
Published: September 12, 2019

The organizing principle of GABAB receptor complexes: Physiological and pharmacological implications.

The organizing principle of GABAB receptor complexes: Physiological and pharmacological implications.

Journal: Basic & clinical pharmacology & toxicology
Published: January 18, 2019

Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.

Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.

Journal: Nature communications
Published: July 06, 2018

KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABAB Receptor-Induced K+ Currents.

KCTD Hetero-oligomers Confer Unique Kinetic Properties on Hippocampal GABAB Receptor-Induced K+ Currents.

Journal: The Journal of neuroscience : the official journal of the Society for Neuroscience
Published: July 08, 2016
Showing 1-12 of 18

Last Updated: 09/26/2026