Thorsten Sadowski

Frankfurt Am Main, HE, Germany

Last Updated: 09/26/2026

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Found 15 publications

Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney.

Hyperpolarized pyruvate to measure the influence of PKM2 activation on glucose metabolism in the healthy kidney.

Journal: NMR in biomedicine

Published: February 24, 2021

Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis.

Hepatocyte TLR4 triggers inter-hepatocyte Jagged1/Notch signaling to determine NASH-induced fibrosis.

Journal: Science translational medicine

Published: August 04, 2020

Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice.

Cathepsin A contributes to left ventricular remodeling by degrading extracellular superoxide dismutase in mice.

Journal: The Journal of biological chemistry

Published: March 20, 2020

Objective and subjective reduction of cellulite volume using a localized vibrational massage device in a 24-week randomized intra-individual single-blind regression study.

Objective and subjective reduction of cellulite volume using a localized vibrational massage device in a 24-week randomized intra-individual single-blind regression study.

Journal: International journal of cosmetic science

Published: November 21, 2019

Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy.

Characterization of Glycolytic Enzymes and Pyruvate Kinase M2 in Type 1 and 2 Diabetic Nephropathy.

Journal: Diabetes care

Published: December 18, 2018

Cathepsin A Mediates Ventricular Remote Remodeling and Atrial Cardiomyopathy in Rats With Ventricular Ischemia/Reperfusion.

Cathepsin A Mediates Ventricular Remote Remodeling and Atrial Cardiomyopathy in Rats With Ventricular Ischemia/Reperfusion.

Journal: JACC. Basic to translational science

Published: September 10, 2018

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.

Pyruvate kinase M2 activation may protect against the progression of diabetic glomerular pathology and mitochondrial dysfunction.

Journal: Nature medicine

Published: January 22, 2017

Proteomic Profiling of Cardiomyocyte-Specific Cathepsin A Overexpression Links Cathepsin A to the Oxidative Stress Response.

Proteomic Profiling of Cardiomyocyte-Specific Cathepsin A Overexpression Links Cathepsin A to the Oxidative Stress Response.

Journal: Journal of proteome research

Published: July 20, 2016

Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels.

Cathepsin A inhibition attenuates myocardial infarction-induced heart failure on the functional and proteomic levels.

Journal: Journal of translational medicine

Published: December 17, 2015

Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats.

Cathepsin A mediates susceptibility to atrial tachyarrhythmia and impairment of atrial emptying function in Zucker diabetic fatty rats.

Journal: Cardiovascular research

Published: November 13, 2015

Tolerability, safety, and pharmacokinetics of the novel cathepsin A inhibitor SAR164653 in healthy subjects.

Tolerability, safety, and pharmacokinetics of the novel cathepsin A inhibitor SAR164653 in healthy subjects.

Journal: Clinical pharmacology in drug development

Published: November 25, 2014

Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases.

Crystal structure of cathepsin A, a novel target for the treatment of cardiovascular diseases.

Journal: Biochemical and biophysical research communications

Published: January 30, 2014

Showing 1-12 of 15

Last Updated: 09/26/2026