Thorsten Schaefer

Basel, BS, Switzerland

Last Updated: 09/26/2026

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Found 18 publications

A conserved VPS34-PIKfyve-TRPML1-myosin II axis regulates the speed of amoeboid cell migration.

A conserved VPS34-PIKfyve-TRPML1-myosin II axis regulates the speed of amoeboid cell migration.

Journal: EMBO reports
Published: December 01, 2025

Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling.

Rapid, potent, and persistent covalent chemical probes to deconvolute PI3Kα signaling.

Journal: Chemical science
Published: August 14, 2024

Screening and surveillance recommendations for central nervous system hemangioblastomas in pediatric patients with Von Hippel-Lindau disease.

Screening and surveillance recommendations for central nervous system hemangioblastomas in pediatric patients with Von Hippel-Lindau disease.

Journal: Journal of neuro-oncology
Published: March 07, 2024

Correction: A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα.

Correction: A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα.

Journal: Chemical science
Published: January 02, 2024

A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα.

A high affinity pan-PI3K binding module supports selective targeted protein degradation of PI3Kα.

Journal: Chemical science
Published: September 01, 2023

Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fate.

Nuclear and cytosolic fractions of SOX2 synergize as transcriptional and translational co-regulators of cell fate.

Journal: Cell reports
Published: July 14, 2023

Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor.

Investigation of morpholine isosters for the development of a potent, selective and metabolically stable mTOR kinase inhibitor.

Journal: European journal of medicinal chemistry
Published: September 28, 2022

SRP54 mutations induce congenital neutropenia via dominant-negative effects on XBP1 splicing.

SRP54 mutations induce congenital neutropenia via dominant-negative effects on XBP1 splicing.

Journal: Blood
Published: July 10, 2020

SOX2 and p53 Expression Control Converges in PI3K/AKT Signaling with Versatile Implications for Stemness and Cancer.

SOX2 and p53 Expression Control Converges in PI3K/AKT Signaling with Versatile Implications for Stemness and Cancer.

Journal: International journal of molecular sciences
Published: May 29, 2020

Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion.

Publisher Correction: Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion.

Journal: Nature
Published: August 02, 2019

SOX2 protein biochemistry in stemness, reprogramming, and cancer: the PI3K/AKT/SOX2 axis and beyond.

SOX2 protein biochemistry in stemness, reprogramming, and cancer: the PI3K/AKT/SOX2 axis and beyond.

Journal: Oncogene
Published: June 16, 2019

Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion.

Absence of NKG2D ligands defines leukaemia stem cells and mediates their immune evasion.

Journal: Nature
Published: June 19, 2018
Showing 1-12 of 18

Last Updated: 09/26/2026