Tian-qi Chen

MOE Key Laboratory Of Gene Function And Regulation, Guangdong Province Key Laboratory Of Pharmaceutical Functional Genes, State Key Laboratory For Biocontrol
Guangzhou, 510275, China

Last Updated: 09/26/2026

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Found 16 publications

RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia.

RBM15B recognizes H3K79me2 to guide selective m6A-modification of mRNA and enhance oncoprotein translation in MLL-r leukemia.

Journal: The EMBO journal

Published: April 14, 2025

Chromatin-associated circRNA ciCRLF3(2) regulates cell differentiation blockage via activating non-homologous end joining-based DNA repair.

Chromatin-associated circRNA ciCRLF3(2) regulates cell differentiation blockage via activating non-homologous end joining-based DNA repair.

Journal: Cell death and differentiation

Published: January 20, 2025

Protocol for investigating phase transition of prion-like proteins in vitro with concentration variation.

Protocol for investigating phase transition of prion-like proteins in vitro with concentration variation.

Journal: STAR protocols

Published: December 18, 2024

lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing.

lncRNAs maintain the functional phase state of nucleolar prion-like protein to facilitate rRNA processing.

Journal: Molecular cell

Published: March 25, 2024

Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins.

Blockade of the lncRNA-DOT1L-LAMP5 axis enhances autophagy and promotes degradation of MLL fusion proteins.

Journal: Experimental hematology & oncology

Published: January 05, 2024

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

METTL3 protects METTL14 from STUB1-mediated degradation to maintain m6 A homeostasis.

Journal: EMBO reports

Published: July 10, 2022

The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1.

The snoRNA-like lncRNA LNC-SNO49AB drives leukemia by activating the RNA-editing enzyme ADAR1.

Journal: Cell discovery

Published: March 26, 2022

N6-methyladenosine methyltransferases: functions, regulation, and clinical potential.

N6-methyladenosine methyltransferases: functions, regulation, and clinical potential.

Journal: Journal of hematology & oncology

Published: June 11, 2021

Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex.

Chromatin-associated orphan snoRNA regulates DNA damage-mediated differentiation via a non-canonical complex.

Journal: Cell reports

Published: May 17, 2021

Correction to: The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.

Correction to: The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.

Journal: Journal of hematology & oncology

Published: March 12, 2021

The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.

The lncRNA LAMP5-AS1 drives leukemia cell stemness by directly modulating DOT1L methyltransferase activity in MLL leukemia.

Journal: Journal of hematology & oncology

Published: April 16, 2020

Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression.

Cis-acting lnc-eRNA SEELA directly binds histone H4 to promote histone recognition and leukemia progression.

Journal: Genome biology

Published: April 04, 2020

Showing 1-12 of 16

Last Updated: 09/26/2026