Tianyun Fan

Chinese Academy Of Medical Sciences And Peking Union Medical College
Beijing, 100050, China

Last Updated: 09/26/2026

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Found 24 publications

Identification of the target ANTXR1 and covalent acylation mechanism of 8-esterified cycloberberines against cancer.

Identification of the target ANTXR1 and covalent acylation mechanism of 8-esterified cycloberberines against cancer.

Journal: European journal of medicinal chemistry

Published: December 29, 2025

Self-assembled nanoparticles from Xiexin Decoction attenuate ulcerative colitis by targeting VDAC1-Mediated NLRP3 inflammasome activation.

Self-assembled nanoparticles from Xiexin Decoction attenuate ulcerative colitis by targeting VDAC1-Mediated NLRP3 inflammasome activation.

Journal: Materials today. Bio

Published: November 27, 2025

Covalent targeting of PSMD14 by Eupalinolide B induces oncoprotein degradation and apoptosis in acute promyelocytic leukemia cells.

Covalent targeting of PSMD14 by Eupalinolide B induces oncoprotein degradation and apoptosis in acute promyelocytic leukemia cells.

Journal: RSC chemical biology

Published: July 31, 2025

Design and synthesis of protoberberine analogues to alleviate LPS-induced acute lung injury by targeting HCK and blocking the HCK-NLRP3 axis.

Design and synthesis of protoberberine analogues to alleviate LPS-induced acute lung injury by targeting HCK and blocking the HCK-NLRP3 axis.

Journal: European journal of medicinal chemistry

Published: July 17, 2025

Eupalinolide B Ameliorates Diabetic Kidney Disease via Inhibition of Cell Division Cycle 37-Mediated Inflammatory Pathways.

Eupalinolide B Ameliorates Diabetic Kidney Disease via Inhibition of Cell Division Cycle 37-Mediated Inflammatory Pathways.

Journal: Journal of the American Society of Nephrology : JASN

Published: June 25, 2025

Immunomodulatory mechanism of Radix Bupleuri polysaccharide on RAW264.7 cells and cyclophosphamide-induced immunosuppressed mice.

Immunomodulatory mechanism of Radix Bupleuri polysaccharide on RAW264.7 cells and cyclophosphamide-induced immunosuppressed mice.

Journal: International journal of biological macromolecules

Published: May 13, 2025

Chelerythrine Chloride Alleviated Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting Glycolytic Pathway Through Targeting Glyceraldehyde-3-Phosphate Dehydrogenase.

Chelerythrine Chloride Alleviated Lipopolysaccharide-Induced Acute Lung Injury by Inhibiting Glycolytic Pathway Through Targeting Glyceraldehyde-3-Phosphate Dehydrogenase.

Journal: Molecules (Basel, Switzerland)

Published: April 19, 2025

Discovery of the Clinical Candidate YY2201 as a Highly Potent and Selective ATR Inhibitor.

Discovery of the Clinical Candidate YY2201 as a Highly Potent and Selective ATR Inhibitor.

Journal: Journal of medicinal chemistry

Published: March 03, 2025

Evolution of 8-esterified cycloberberines as a novel class of antibacterial agents against MDR gram-positive strains by targeting DNA polymerase IIIC.

Evolution of 8-esterified cycloberberines as a novel class of antibacterial agents against MDR gram-positive strains by targeting DNA polymerase IIIC.

Journal: Bioorganic chemistry

Published: February 25, 2025

Effect of daphnetin, the coumarin derivative isolated from Daphne genus, on Helicobacter pylori adhesion to gastric epithelial cells.

Effect of daphnetin, the coumarin derivative isolated from Daphne genus, on Helicobacter pylori adhesion to gastric epithelial cells.

Journal: Phytomedicine : international journal of phytotherapy and phytopharmacology

Published: August 05, 2024

Discovery and evolution of berberine analogues as anti-Helicobacter pylori agents with multi-target mechanisms.

Discovery and evolution of berberine analogues as anti-Helicobacter pylori agents with multi-target mechanisms.

Journal: Bioorganic chemistry

Published: April 10, 2024

Erratum: Author correction to 'Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects' [Acta Pharmaceutica Sinica B 13 (2023) 2138-2151].

Erratum: Author correction to 'Discovery and identification of EIF2AK2 as a direct key target of berberine for anti-inflammatory effects' [Acta Pharmaceutica Sinica B 13 (2023) 2138-2151].

Journal: Acta pharmaceutica Sinica. B

Published: March 15, 2024

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Last Updated: 09/26/2026