Tim Bourne

Oxford Science Park
Oxford, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 17 publications

Corrigendum: An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.

Corrigendum: An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.

Journal: Frontiers in pharmacology

Published: August 12, 2024

Target occupancy biomarker assay development using a conformation-selective antibody against small-molecule-bound TNF.

Target occupancy biomarker assay development using a conformation-selective antibody against small-molecule-bound TNF.

Journal: Bioanalysis

Published: April 07, 2023

Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation.

Differential roles of CTP synthetases CTPS1 and CTPS2 in cell proliferation.

Journal: Life science alliance

Published: March 29, 2023

An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.

An orally available small molecule that targets soluble TNF to deliver anti-TNF biologic-like efficacy in rheumatoid arthritis.

Journal: Frontiers in pharmacology

Published: September 06, 2022

Transitioning EPMA applications in a large multisite teaching hospital.

Transitioning EPMA applications in a large multisite teaching hospital.

Journal: BMJ open quality

Published: November 17, 2021

Codeveloping an effective EMPA to maturity in an acute NHS Trust: an implementer report.

Codeveloping an effective EMPA to maturity in an acute NHS Trust: an implementer report.

Journal: BMJ health & care informatics

Published: August 31, 2021

Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer.

Peri-operative Variables Associated With Prolonged Intensive Care Stay Following Cytoreductive Surgery for Ovarian Cancer.

Journal: Anticancer research

Published: April 22, 2021

MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function.

MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function.

Journal: Immunity

Published: January 14, 2021

Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.

Structural insights into the disruption of TNF-TNFR1 signalling by small molecules stabilising a distorted TNF.

Journal: Nature communications

Published: May 22, 2020

Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.

Impaired lymphocyte function and differentiation in CTPS1-deficient patients result from a hypomorphic homozygous mutation.

Journal: JCI insight

Published: October 04, 2019

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.

Small molecules that inhibit TNF signalling by stabilising an asymmetric form of the trimer.

Journal: Nature communications

Published: April 10, 2019

Efficacy of an Inhaled IL-13 Antibody Fragment in a Model of Chronic Asthma.

Efficacy of an Inhaled IL-13 Antibody Fragment in a Model of Chronic Asthma.

Journal: American journal of respiratory and critical care medicine

Published: June 09, 2018

Showing 1-12 of 17

Last Updated: 09/26/2026