Timothy Harrison

97 Lisburn Road
Belfast, NIR BT97AE, United Kingdom

Last Updated: 09/26/2026

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Found 16 publications

Deubiquitinating Enzyme UCH-L1 Regulates Neuronal Ca2+ Signaling.

Deubiquitinating Enzyme UCH-L1 Regulates Neuronal Ca2+ Signaling.

Journal: ACS chemical neuroscience

Published: September 24, 2025

Chemical- and photo-activation of protein-protein thiol-ene coupling for protein profiling.

Chemical- and photo-activation of protein-protein thiol-ene coupling for protein profiling.

Journal: Communications chemistry

Published: August 19, 2024

Inhibition of AKT enhances chemotherapy efficacy and synergistically interacts with targeting of the Inhibitor of apoptosis proteins in oesophageal adenocarcinoma.

Inhibition of AKT enhances chemotherapy efficacy and synergistically interacts with targeting of the Inhibitor of apoptosis proteins in oesophageal adenocarcinoma.

Journal: Scientific reports

Published: February 02, 2024

USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.

USP7 inhibitors suppress tumour neoangiogenesis and promote synergy with immune checkpoint inhibitors by downregulating fibroblast VEGF.

Journal: Clinical and translational medicine

Published: November 13, 2023

Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.

Identification and development of a subtype-selective allosteric AKT inhibitor suitable for clinical development.

Journal: Scientific reports

Published: March 28, 2022

RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer.

RALB GTPase: a critical regulator of DR5 expression and TRAIL sensitivity in KRAS mutant colorectal cancer.

Journal: Cell death & disease

Published: May 25, 2020

A revised model of TRAIL-R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis.

A revised model of TRAIL-R2 DISC assembly explains how FLIP(L) can inhibit or promote apoptosis.

Journal: EMBO reports

Published: September 10, 2019

Identification and SAR exploration of a novel series of Legumain inhibitors.

Identification and SAR exploration of a novel series of Legumain inhibitors.

Journal: Bioorganic & medicinal chemistry letters

Published: January 07, 2019

Email fraud: The search for psychological predictors of susceptibility.

Email fraud: The search for psychological predictors of susceptibility.

Journal: PloS one

Published: July 30, 2018

Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.

Identification and Structure-Guided Development of Pyrimidinone Based USP7 Inhibitors.

Journal: ACS medicinal chemistry letters

Published: December 08, 2017

Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily.

Identification and Characterization of Dual Inhibitors of the USP25/28 Deubiquitinating Enzyme Subfamily.

Journal: ACS chemical biology

Published: November 14, 2017

Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.

Discovery and characterization of highly potent and selective allosteric USP7 inhibitors.

Journal: Nature chemical biology

Published: February 27, 2017

Showing 1-12 of 16

Last Updated: 09/26/2026