Timothy R. Hughes

Heath Park
Cardiff, WLS CF144XN, United Kingdom

Last Updated: 09/26/2026

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Found 41 publications

Anti-Atherogenic Actions of Pomegranate Polyphenol Punicalagin and Its Metabolites: In Vitro Effects on Vascular Cells and In Vivo Atheroprotection by Urolithin A via Anti-Inflammatory and Plaque-Stabilising Mechanisms.

Anti-Atherogenic Actions of Pomegranate Polyphenol Punicalagin and Its Metabolites: In Vitro Effects on Vascular Cells and In Vivo Atheroprotection by Urolithin A via Anti-Inflammatory and Plaque-Stabilising Mechanisms.

Journal: Antioxidants (Basel, Switzerland)

Published: March 05, 2026

The impact of the Lab4 probiotic on neurodegenerative processes in a murine Alzheimer's disease model.

The impact of the Lab4 probiotic on neurodegenerative processes in a murine Alzheimer's disease model.

Journal: Frontiers in neuroscience

Published: January 19, 2026

Resveratrol Mediates Anti-Atherogenic Actions In Vitro and in LDL Receptor-Deficient Mice Fed a High-Fat Diet via Antioxidant, Anti-Inflammatory and Plaque-Stabilising Activities.

Resveratrol Mediates Anti-Atherogenic Actions In Vitro and in LDL Receptor-Deficient Mice Fed a High-Fat Diet via Antioxidant, Anti-Inflammatory and Plaque-Stabilising Activities.

Journal: Antioxidants (Basel, Switzerland)

Published: November 17, 2025

Severe necrotizing soft tissue infections (SENSEI) study: Protocol for a multi-centered audit.

Severe necrotizing soft tissue infections (SENSEI) study: Protocol for a multi-centered audit.

Journal: JPRAS open

Published: July 16, 2025

Absence of complement terminal pathway activity in C6-deficient mice prolongs survival in a mouse model of severe malarial infection.

Absence of complement terminal pathway activity in C6-deficient mice prolongs survival in a mouse model of severe malarial infection.

Journal: Immunobiology

Published: June 01, 2025

Cytomegalovirus-induced T cell responses accelerate Alzheimer's disease progression in mice.

Cytomegalovirus-induced T cell responses accelerate Alzheimer's disease progression in mice.

Journal: Brain : a journal of neurology

Published: April 11, 2025

The schizophrenia-associated gene CSMD1 encodes a complement classical pathway inhibitor predominantly expressed by astrocytes and at synapses in mice and humans.

The schizophrenia-associated gene CSMD1 encodes a complement classical pathway inhibitor predominantly expressed by astrocytes and at synapses in mice and humans.

Journal: Brain, behavior, and immunity

Published: November 08, 2024

From complement to complosome in non-alcoholic fatty liver disease: When location matters.

From complement to complosome in non-alcoholic fatty liver disease: When location matters.

Journal: Liver international : official journal of the International Association for the Study of the Liver

Published: September 10, 2023

Therapeutic targeting of chronic kidney disease-associated DAMPs differentially contributing to vascular pathology.

Therapeutic targeting of chronic kidney disease-associated DAMPs differentially contributing to vascular pathology.

Journal: Frontiers in immunology

Published: June 15, 2023

Assessment of Lab4P Probiotic Effects on Cognition in 3xTg-AD Alzheimer's Disease Model Mice and the SH-SY5Y Neuronal Cell Line.

Assessment of Lab4P Probiotic Effects on Cognition in 3xTg-AD Alzheimer's Disease Model Mice and the SH-SY5Y Neuronal Cell Line.

Journal: International journal of molecular sciences

Published: December 17, 2022

(+)-Catechin Attenuates Multiple Atherosclerosis-Associated Processes In Vitro, Modulates Disease-Associated Risk Factors in C57BL/6J Mice and Reduces Atherogenesis in LDL Receptor Deficient Mice by Inhibiting Inflammation and Increasing Markers of Plaque Stability.

(+)-Catechin Attenuates Multiple Atherosclerosis-Associated Processes In Vitro, Modulates Disease-Associated Risk Factors in C57BL/6J Mice and Reduces Atherogenesis in LDL Receptor Deficient Mice by Inhibiting Inflammation and Increasing Markers of Plaque Stability.

Journal: Molecular nutrition & food research

Published: October 20, 2022

Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice.

Therapeutic Intervention with Anti-Complement Component 5 Antibody Does Not Reduce NASH but Does Attenuate Atherosclerosis and MIF Concentrations in Ldlr-/-.Leiden Mice.

Journal: International journal of molecular sciences

Published: July 28, 2022

Showing 1-12 of 41

Last Updated: 09/26/2026