Timothy R. Billiar

Timothy R. Billiar

General Surgery
3601 5th Avenue, Suite 6B
Pittsburgh, PA 15213

Last Updated: 09/26/2026

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Found 382 publications

Metabolic-epigenetic rewiring of CCR5hi monocytes sustains long-term trained immunity against lethal sepsis.

Metabolic-epigenetic rewiring of CCR5hi monocytes sustains long-term trained immunity against lethal sepsis.

Journal: Science advances
Published: August 21, 2026

Corrigendum to Myeloperoxidase-anchored ENO1 mediates neutrophil extracellular trap DNA to enhance Treg differentiation via IFITM2 during sepsis.

Corrigendum to Myeloperoxidase-anchored ENO1 mediates neutrophil extracellular trap DNA to enhance Treg differentiation via IFITM2 during sepsis.

Journal: The Journal of clinical investigation
Published: May 01, 2026

NOS2 and COX2 impact the spatial landscape of CD8+ T cells in ER-breast cancer, providing novel mechanistic insight that drives tumor progression and poor survival.

NOS2 and COX2 impact the spatial landscape of CD8+ T cells in ER-breast cancer, providing novel mechanistic insight that drives tumor progression and poor survival.

Journal: Redox biology
Published: March 18, 2026

Nitric oxide-driven Warburg reprogramming at the NOS2-COX2 axis: An integrative engine of cancer hallmarks.

Nitric oxide-driven Warburg reprogramming at the NOS2-COX2 axis: An integrative engine of cancer hallmarks.

Journal: Redox biology
Published: March 12, 2026

Targeting TRAF7: a new approach to modulate AKT in acute lung injury.

Targeting TRAF7: a new approach to modulate AKT in acute lung injury.

Journal: Science bulletin
Published: February 15, 2026

Hallmarks of the multidimensional immune response to trauma in humans.

Hallmarks of the multidimensional immune response to trauma in humans.

Journal: Nature immunology
Published: February 12, 2026

Whole blood storage time impairs clot strength with minimal change in functional fibrinogen concentration.

Whole blood storage time impairs clot strength with minimal change in functional fibrinogen concentration.

Journal: Transfusion
Published: December 01, 2025

Correction: Plumbagin protects mice from lethal Sepsis by modulating immunometabolism upstream of PKM2.

Correction: Plumbagin protects mice from lethal Sepsis by modulating immunometabolism upstream of PKM2.

Journal: Molecular medicine (Cambridge, Mass.)
Published: July 27, 2025

Author Correction: PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.

Author Correction: PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.

Journal: Nature communications
Published: July 04, 2025

Multi-modal single-cell sequencing reveals network transition in circulating monocytes that aligns with faster recovery in patients with trauma and favours a response to M-CSF.

Multi-modal single-cell sequencing reveals network transition in circulating monocytes that aligns with faster recovery in patients with trauma and favours a response to M-CSF.

Journal: EBioMedicine
Published: June 11, 2025

Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis.

Nuclear localization of STING1 competes with canonical signaling to activate AHR for commensal and intestinal homeostasis.

Journal: Immunity
Published: May 29, 2025

Gasdermin D drives the systemic storm and mortality after trauma with hemorrhage to a greater degree in biological females than males.

Gasdermin D drives the systemic storm and mortality after trauma with hemorrhage to a greater degree in biological females than males.

Journal: Science translational medicine
Published: May 28, 2025
Showing 1-12 of 382

Last Updated: 09/26/2026