Tjasa Gorican

Ljubljana, 1000, Slovenia

Last Updated: 09/26/2026

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Found 10 publications

Are the pKa values of free fatty acids in aqueous solution abnormally high? An NMR and computational perspective.

Are the pKa values of free fatty acids in aqueous solution abnormally high? An NMR and computational perspective.

Journal: Chemical communications (Cambridge, England)

Published: November 25, 2025

Unveiling the Solvent Effect: DMSO Interaction with Human Nerve Growth Factor and Its Implications for Drug Discovery.

Unveiling the Solvent Effect: DMSO Interaction with Human Nerve Growth Factor and Its Implications for Drug Discovery.

Journal: Molecules (Basel, Switzerland)

Published: June 09, 2025

Insights into the Allosteric Regulation of Human Hsp90 Revealed by NMR Spectroscopy.

Insights into the Allosteric Regulation of Human Hsp90 Revealed by NMR Spectroscopy.

Journal: Biomolecules

Published: November 14, 2024

Phytochemical Analysis and Biological Evaluation of Carob Leaf (Ceratonia siliqua L.) Crude Extracts Using NMR and Mass Spectroscopic Techniques.

Phytochemical Analysis and Biological Evaluation of Carob Leaf (Ceratonia siliqua L.) Crude Extracts Using NMR and Mass Spectroscopic Techniques.

Journal: Molecules (Basel, Switzerland)

Published: October 21, 2024

Discovery of new Hsp90-Cdc37 protein-protein interaction inhibitors: in silico screening and optimization of anticancer activity.

Discovery of new Hsp90-Cdc37 protein-protein interaction inhibitors: in silico screening and optimization of anticancer activity.

Journal: RSC advances

Published: August 13, 2024

First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo.

First dual inhibitors of human topoisomerase IIα and Hsp90 C-terminal domain inhibit the growth of Ewing sarcoma in vitro and in vivo.

Journal: Bioorganic chemistry

Published: August 01, 2024

Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders.

Hiding in plain sight: Optimizing topoisomerase IIα inhibitors into Hsp90β selective binders.

Journal: European journal of medicinal chemistry

Published: May 23, 2024

Simulation- and AI-directed optimization of 4,6-substituted 1,3,5-triazin-2(1H)-ones as inhibitors of human DNA topoisomerase IIα.

Simulation- and AI-directed optimization of 4,6-substituted 1,3,5-triazin-2(1H)-ones as inhibitors of human DNA topoisomerase IIα.

Journal: Computational and structural biotechnology journal

Published: May 03, 2024

Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency.

Exploration and optimisation of structure-activity relationships of new triazole-based C-terminal Hsp90 inhibitors towards in vivo anticancer potency.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: January 31, 2024

Synthesis and kinetic characterization of hyperbolic inhibitors of human cathepsins K and S based on a succinimide scaffold.

Synthesis and kinetic characterization of hyperbolic inhibitors of human cathepsins K and S based on a succinimide scaffold.

Journal: Bioorganic chemistry

Published: March 25, 2021

Showing 1-10 of 10

Last Updated: 09/26/2026