Tobias Obser
Hamburg, HH, Germany
Last Updated: 09/26/2026
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Found 41 publications
Medulloblastoma in children with Fanconi anemia: Association with FA-D1/FA-N, SHH type and poor survival independent of treatment strategies.
Journal: Neuro-oncology
Published: June 26, 2024
The search for the underlying mutations causing VWD in 13 Venezuelan families.
Journal: Thrombosis research
Published: June 01, 2023
Heparan sulfate dependent binding of plasmatic von Willebrand factor to blood circulating melanoma cells attenuates metastasis.
Journal: Matrix biology : journal of the International Society for Matrix Biology
Published: January 13, 2022
A conformational transition of the D'D3 domain primes von Willebrand factor for multimerization.
Journal: Blood advances
Published: January 04, 2022
The activity of the intrinsically water-soluble enzyme ADAMTS13 correlates with the membrane state when bound to a phospholipid bilayer.
Journal: Scientific reports
Published: August 05, 2021
Gain-of-Function Variant p.Pro2555Arg of von Willebrand Factor Increases Aggregate Size through Altering Stem Dynamics.
Journal: Thrombosis and haemostasis
Published: December 31, 2020
Platelet adhesion and aggregate formation controlled by immobilised and soluble VWF.
Journal: BMC molecular and cell biology
Published: February 23, 2020
Upshaw-Schulman syndrome-associated ADAMTS13 variants possess proteolytic activity at the surface of endothelial cells and in simulated circulation.
Journal: PloS one
Published: January 17, 2020
Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor.
Journal: Proceedings of the National Academy of Sciences of the United States of America
Published: August 30, 2019
Evidence for the Misfolding of the A1 Domain within Multimeric von Willebrand Factor in Type 2 von Willebrand Disease.
Journal: Journal of molecular biology
Published: July 15, 2019
Alteration in GPIIb/IIIa Binding of VWD-Associated von Willebrand Factor Variants with C-Terminal Missense Mutations.
Journal: Thrombosis and haemostasis
Published: April 30, 2019
Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow.
Journal: Frontiers in microbiology
Published: November 06, 2018
Last Updated: 09/26/2026