Tohru Takaki

London, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 12 publications

Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity.

Distinct ATRX functions cooperate with 9-1-1 and CST complexes to safeguard replication and telomere integrity.

Journal: Nature structural & molecular biology

Published: September 08, 2025

EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers.

EXO1 as a therapeutic target for Fanconi Anaemia, ZRSR2 and BRCA1-A complex deficient cancers.

Journal: Nature communications

Published: June 26, 2024

Micronuclei induced by radiation, replication stress, or chromosome segregation errors do not activate cGAS-STING.

Micronuclei induced by radiation, replication stress, or chromosome segregation errors do not activate cGAS-STING.

Journal: Molecular cell

Published: January 02, 2024

HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51.

HELQ is a dual-function DSB repair enzyme modulated by RPA and RAD51.

Journal: Nature

Published: June 02, 2021

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.

Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD.

Journal: Molecular cell

Published: May 11, 2020

Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.

Plk1 regulates contraction of postmitotic smooth muscle cells and is required for vascular homeostasis.

Journal: Nature medicine

Published: November 17, 2016

Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability.

Actomyosin drives cancer cell nuclear dysmorphia and threatens genome stability.

Journal: Nature communications

Published: August 20, 2016

A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling.

A Polar and Nucleotide-Dependent Mechanism of Action for RAD51 Paralogs in RAD51 Filament Remodeling.

Journal: Molecular cell

Published: July 05, 2016

Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells.

Confinement and low adhesion induce fast amoeboid migration of slow mesenchymal cells.

Journal: Cell

Published: May 02, 2014

Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis.

Centralspindlin links the mitotic spindle to the plasma membrane during cytokinesis.

Journal: Nature

Published: May 15, 2012

Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C.

Dephosphorylation of Cdc20 is required for its C-box-dependent activation of the APC/C.

Journal: The EMBO journal

Published: January 24, 2012

Targeting of the RhoGEF Ect2 to the equatorial membrane controls cleavage furrow formation during cytokinesis.

Targeting of the RhoGEF Ect2 to the equatorial membrane controls cleavage furrow formation during cytokinesis.

Journal: Developmental cell

Published: October 10, 2011

Showing 1-12 of 12

Last Updated: 09/26/2026