Tom A. Brown
South Parks Rd
Oxford, ENG, United Kingdom
Oxford, ENG, United Kingdom
Last Updated: 09/26/2026
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Found 117 publications
A versatile strategy for oligonucleotide functionalization via on-support phosphitylation.
Journal: Nature chemistry
Published: December 19, 2025
Non-enzymatic conversion of RNA sequence information into DNA by squaramide ligation for accurate RNA quantification.
Journal: Communications chemistry
Published: December 14, 2025
Molecular basis for CSB stimulation of the SNM1A DNA repair nuclease.
Journal: Research square
Published: December 03, 2025
Enzymatic Synthesis of Modified RNA Containing 5-Methyl- or 5-Ethylpyrimidines or Substituted 7-Deazapurines and Influence of the Modifications on Stability, Translation, and CRISPR-Cas9 Cleavage.
Journal: ACS chemical biology
Published: November 06, 2025
Biophysical and biological properties of splice-switching oligonucleotides and click conjugates containing LNA-phosphothiotriester linkages.
Journal: Nucleic acids research
Published: August 11, 2025
Enhancing cap-independent translation of linear mRNA.
Journal: Nature communications
Published: August 05, 2025
Synthesis, Biological Activity, and Molecular Dynamics Simulations of LNA-Charge Neutral Linkages for Enhanced Splice-Switching Antisense Oligonucleotides.
Journal: Angewandte Chemie (International ed. in English)
Published: May 24, 2025
Molecular insights into the stimulation of SNM1A nuclease activity by CSB during interstrand crosslink processing.
Journal: bioRxiv : the preprint server for biology
Published: September 16, 2024
Modular and automated synthesis of oligonucleotide-small molecule conjugates for cathepsin B mediated traceless release of payloads.
Journal: RSC chemical biology
Published: May 23, 2024
Enhancing single-cell transcriptomics using interposed anchor oligonucleotide sequences.
Journal: Communications biology
Published: May 21, 2024
Last Updated: 09/26/2026