Tom Lesluyes

Bordeaux, 33000, France

Last Updated: 09/26/2026

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Found 52 publications

Scalable subclonal reconstruction of cancer cells in DNA sequencing data using a penalized likelihood model.

Scalable subclonal reconstruction of cancer cells in DNA sequencing data using a penalized likelihood model.

Journal: bioRxiv : the preprint server for biology

Published: May 18, 2026

Profiling the genomic landscape and evolutionary history of polyploid giant cancer cells in undifferentiated pleomorphic sarcomas.

Profiling the genomic landscape and evolutionary history of polyploid giant cancer cells in undifferentiated pleomorphic sarcomas.

Journal: Cancer letters

Published: June 30, 2025

Loss of IDH1 and IDH2 mutations during the evolution of metastatic chondrosarcoma.

Loss of IDH1 and IDH2 mutations during the evolution of metastatic chondrosarcoma.

Journal: Genome biology

Published: April 08, 2025

Subclonal mutation load predicts survival and response to immunotherapy in cancers with low to moderate tumor mutation burden.

Subclonal mutation load predicts survival and response to immunotherapy in cancers with low to moderate tumor mutation burden.

Journal: bioRxiv : the preprint server for biology

Published: July 15, 2024

Reconstructing oral cavity tumor evolution through brush biopsy.

Reconstructing oral cavity tumor evolution through brush biopsy.

Journal: Scientific reports

Published: February 11, 2024

The History of Chromosomal Instability in Genome-Doubled Tumors.

The History of Chromosomal Instability in Genome-Doubled Tumors.

Journal: Cancer discovery

Published: October 25, 2023

Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring.

Evolution of chromosome-arm aberrations in breast cancer through genetic network rewiring.

Journal: Cell reports

Published: September 01, 2023

Age-specific induction of mutant p53 drives clonal hematopoiesis and acute myeloid leukemia in adult mice.

Age-specific induction of mutant p53 drives clonal hematopoiesis and acute myeloid leukemia in adult mice.

Journal: Cell reports. Medicine

Published: August 16, 2023

Genomic profile analysis of leiomyomas with bizarre nuclei and fumarate hydratase deficient leiomyomas: Strengths, weaknesses, and limitations of array-CGH interpretation.

Genomic profile analysis of leiomyomas with bizarre nuclei and fumarate hydratase deficient leiomyomas: Strengths, weaknesses, and limitations of array-CGH interpretation.

Journal: Genes, chromosomes & cancer

Published: June 05, 2023

Analysis of the Peritumoral Tissue Unveils Cellular Changes Associated with a High Risk of Recurrence.

Analysis of the Peritumoral Tissue Unveils Cellular Changes Associated with a High Risk of Recurrence.

Journal: Cancers

Published: May 15, 2023

Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.

Cancer origin tracing and timing in two high-risk prostate cancers using multisample whole genome analysis: prospects for personalized medicine.

Journal: Genome medicine

Published: April 13, 2023

Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression.

Spatiotemporal genomic profiling of intestinal metaplasia reveals clonal dynamics of gastric cancer progression.

Journal: Cancer cell

Published: March 17, 2023

Showing 1-12 of 52

Last Updated: 09/26/2026