Tom Reynders
Brussels, BRU, Belgium
Last Updated: 09/26/2026
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Found 15 publications
First-in-human safety and pharmacokinetics of MK-7602, the antimalarial inhibitor of plasmepsins IX/X, in single- and multiple-ascending-dose studies.
Journal: Antimicrobial agents and chemotherapy
Published: January 14, 2026
Phase 1 Study Evaluating the Effects of Single-Dose Frespaciguat, an Inhaled Soluble Guanylate Cyclase Stimulator, Co-administered with Multiple-Dose Sildenafil on Systemic Hemodynamics.
Journal: Clinical pharmacology in drug development
Published: November 19, 2025
Antiretroviral Activity, Pharmacokinetics, and Safety of MK-8527, an Oral Nucleoside Reverse Transcriptase Translocation Inhibitor, in Adults With HIV-1 Who Had Not Previously Taken Antiretroviral Agents: Results From 2 Open-Label, Phase 1 Studies.
Journal: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Published: August 20, 2025
Safety and Pharmacokinetics of MK-8527 in Adults Without HIV.
Journal: Clinical and translational science
Published: February 11, 2025
Phase 1 Study of MK-5475, an Inhaled Soluble Guanylate Cyclase Stimulator, in Participants with Pulmonary Hypertension Associated with Chronic Obstructive Pulmonary Disease.
Journal: International journal of chronic obstructive pulmonary disease
Published: January 18, 2024
A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial of Radiopaque Islatravir-Eluting Subdermal Implants for Pre-exposure Prophylaxis Against HIV-1 Infection.
Journal: Journal of acquired immune deficiency syndromes (1999)
Published: May 24, 2022
Safety and pharmacokinetics of islatravir subdermal implant for HIV-1 pre-exposure prophylaxis: a randomized, placebo-controlled phase 1 trial.
Journal: Nature medicine
Published: November 20, 2020
Ubrogepant Is Not Associated With Clinically Meaningful Elevations of Alanine Aminotransferase in Healthy Adult Males.
Journal: Clinical and translational science
Published: August 12, 2019
Preclinical Safety Evaluation and Human Dosimetry of [18F]MK-6240, a Novel PET Tracer for Imaging Neurofibrillary Tangles.
Journal: Molecular imaging and biology
Published: May 22, 2019
Brain Imaging of Alzheimer Dementia Patients and Elderly Controls with 18F-MK-6240, a PET Tracer Targeting Neurofibrillary Tangles.
Journal: Journal of nuclear medicine : official publication, Society of Nuclear Medicine
Published: January 12, 2018
Discovery and Clinical Evaluation of MK-8150, A Novel Nitric Oxide Donor With a Unique Mechanism of Nitric Oxide Release.
Journal: Journal of the American Heart Association
Published: August 27, 2016
Last Updated: 09/26/2026