Tom Skaria

Kozhikode, KL, India

Last Updated: 09/26/2026

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Found 21 publications

ADAM17 inhibition by the common antihistamine drug fexofenadine dampens soluble proinflammatory TNF-α release.

ADAM17 inhibition by the common antihistamine drug fexofenadine dampens soluble proinflammatory TNF-α release.

Journal: Biochemical pharmacology
Published: February 25, 2026

Paracrine signaling mediators of vascular endothelial barrier dysfunction in sepsis: implications for therapeutic targeting.

Paracrine signaling mediators of vascular endothelial barrier dysfunction in sepsis: implications for therapeutic targeting.

Journal: Tissue barriers
Published: May 16, 2025

Mechanistic insights into the cofactor binding dynamics and interaction between telmisartan and human thiopurine S-methyltransferase.

Mechanistic insights into the cofactor binding dynamics and interaction between telmisartan and human thiopurine S-methyltransferase.

Journal: Journal of pharmaceutical sciences
Published: April 08, 2025

Cathepsin S: A key drug target and signalling hub in immune system diseases.

Cathepsin S: A key drug target and signalling hub in immune system diseases.

Journal: International immunopharmacology
Published: March 10, 2025

Novel Insights Into the Dynamic Conformational Transitions and Active Site Plasticity of Human Immunoregulatory Cathepsin S.

Novel Insights Into the Dynamic Conformational Transitions and Active Site Plasticity of Human Immunoregulatory Cathepsin S.

Journal: Proteins
Published: January 31, 2025

The developmental and inflammatory disease target protein ADAM17 is vulnerable to off-target interaction by the drug eltrombopag: Insights from molecular modeling.

The developmental and inflammatory disease target protein ADAM17 is vulnerable to off-target interaction by the drug eltrombopag: Insights from molecular modeling.

Journal: Computers in biology and medicine
Published: September 18, 2024

Soluble vascular endothelial glycocalyx proteoglycans as potential therapeutic targets in inflammatory diseases.

Soluble vascular endothelial glycocalyx proteoglycans as potential therapeutic targets in inflammatory diseases.

Journal: Immunology and cell biology
Published: October 10, 2023

Biomolecular interactions between the antibacterial ceftolozane and the human inflammatory disease target ADAM17: a drug repurposing study.

Biomolecular interactions between the antibacterial ceftolozane and the human inflammatory disease target ADAM17: a drug repurposing study.

Journal: Journal of biomolecular structure & dynamics
Published: October 06, 2023

Novel regulators of airway epithelial barrier function during inflammation: potential targets for drug repurposing.

Novel regulators of airway epithelial barrier function during inflammation: potential targets for drug repurposing.

Journal: Expert opinion on therapeutic targets
Published: January 27, 2022

The Neuropeptide α-Calcitonin Gene-Related Peptide as the Mediator of Beneficial Effects of Exercise in the Cardiovascular System.

The Neuropeptide α-Calcitonin Gene-Related Peptide as the Mediator of Beneficial Effects of Exercise in the Cardiovascular System.

Journal: Frontiers in physiology
Published: November 30, 2021

Improved method for surgical induction of chronic hypertension in mice.

Improved method for surgical induction of chronic hypertension in mice.

Journal: Biology open
Published: November 23, 2021

Transcriptional Regulation of Drug Metabolizing CYP Enzymes by Proinflammatory Wnt5A Signaling in Human Coronary Artery Endothelial Cells.

Transcriptional Regulation of Drug Metabolizing CYP Enzymes by Proinflammatory Wnt5A Signaling in Human Coronary Artery Endothelial Cells.

Journal: Frontiers in pharmacology
Published: October 20, 2020
Showing 1-12 of 21

Last Updated: 09/26/2026