Tomas Aragon

55 Pio XII Street
Pamplona, NC 31008, Spain

Last Updated: 09/26/2026

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Found 24 publications

DNA damage/p53, innate immune, and unfolded protein responses are activated in primate liver after toxic, high-dose AAV-SMN1 delivery.

DNA damage/p53, innate immune, and unfolded protein responses are activated in primate liver after toxic, high-dose AAV-SMN1 delivery.

Journal: Molecular therapy. Advances

Published: August 04, 2025

GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model.

GCN2 inhibition reduces mutant SOD1 clustering and toxicity and delays disease progression in an amyotrophic lateral sclerosis mouse model.

Journal: Translational neurodegeneration

Published: August 08, 2024

Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model.

Pharmacological inhibition of the integrated stress response accelerates disease progression in an amyotrophic lateral sclerosis mouse model.

Journal: British journal of pharmacology

Published: March 08, 2023

Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.

Author Correction: Defective HNF4alpha-dependent gene expression as a driver of hepatocellular failure in alcoholic hepatitis.

Journal: Nature communications

Published: February 10, 2023

Stabilization of 14-3-3 protein-protein interactions with Fusicoccin-A decreases alpha-synuclein dependent cell-autonomous death in neuronal and mouse models.

Stabilization of 14-3-3 protein-protein interactions with Fusicoccin-A decreases alpha-synuclein dependent cell-autonomous death in neuronal and mouse models.

Journal: Neurobiology of disease

Published: January 31, 2023

The Role and Therapeutic Potential of the Integrated Stress Response in Amyotrophic Lateral Sclerosis.

The Role and Therapeutic Potential of the Integrated Stress Response in Amyotrophic Lateral Sclerosis.

Journal: International journal of molecular sciences

Published: June 13, 2022

Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1α.

Live imaging of the co-translational recruitment of XBP1 mRNA to the ER and its processing by diffuse, non-polarized IRE1α.

Journal: eLife

Published: November 15, 2021

Linking the Expression of Therapeutic Genes to Unfolded Protein Response: A New Option for Anti-Hepatitis B Virus Gene Therapy.

Linking the Expression of Therapeutic Genes to Unfolded Protein Response: A New Option for Anti-Hepatitis B Virus Gene Therapy.

Journal: Human gene therapy

Published: November 20, 2020

The importance of naturally attenuated SARS-CoV-2in the fight against COVID-19.

The importance of naturally attenuated SARS-CoV-2in the fight against COVID-19.

Journal: Environmental microbiology

Published: April 22, 2020

Maturation of NAA20 Aminoterminal End Is Essential to Assemble NatB N-Terminal Acetyltransferase Complex.

Maturation of NAA20 Aminoterminal End Is Essential to Assemble NatB N-Terminal Acetyltransferase Complex.

Journal: Journal of molecular biology

Published: April 06, 2020

Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets.

Proteostasis disturbances and endoplasmic reticulum stress contribute to polycystic liver disease: New therapeutic targets.

Journal: Liver international : official journal of the International Association for the Study of the Liver

Published: December 17, 2019

Recent advances in signal integration mechanisms in the unfolded protein response.

Recent advances in signal integration mechanisms in the unfolded protein response.

Journal: F1000Research

Published: October 22, 2019

Showing 1-12 of 24

Last Updated: 09/26/2026