Tomoya Yamada

Tokyo, 1046111, Japan

Last Updated: 09/26/2026

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Found 50 publications

The use of cultured human hepatocytes as a test system to evaluate cell proliferation as a key event in nongenotoxic carcinogenesis.

The use of cultured human hepatocytes as a test system to evaluate cell proliferation as a key event in nongenotoxic carcinogenesis.

Journal: Archives of toxicology

Published: March 13, 2026

Response to the Letter from Professor C. R. Wolf and colleagues concerning CRT, 55: 549-586, 2025: The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome-proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation.

Response to the Letter from Professor C. R. Wolf and colleagues concerning CRT, 55: 549-586, 2025: The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome-proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation.

Journal: Critical reviews in toxicology

Published: January 19, 2026

The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation.

The modes of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR) and the peroxisome proliferator-activated receptor alpha (PPARα) are not relevant to human cancer risk: an updated critical evaluation.

Journal: Critical reviews in toxicology

Published: June 27, 2025

Chemical-induced perinatal thyroid hormone disruption and brain developmental adversity: status of efforts aimed at developing new evaluation methods

Chemical-induced perinatal thyroid hormone disruption and brain developmental adversity: status of efforts aimed at developing new evaluation methods

Journal: Nihon yakurigaku zasshi. Folia pharmacologica Japonica

Published: March 02, 2025

An evaluation of the human relevance of the hepatocellular tumors observed in mice treated with synthetic fungicide, pyridachlometyl, based on mode of action.

An evaluation of the human relevance of the hepatocellular tumors observed in mice treated with synthetic fungicide, pyridachlometyl, based on mode of action.

Journal: Archives of toxicology

Published: February 12, 2025

Perinatal maternal exposure to high-dose sodium phenobarbital in the modified Comparative Thyroid Assay: no significant reduction in thyroid hormones in pups despite notable effects in dams.

Perinatal maternal exposure to high-dose sodium phenobarbital in the modified Comparative Thyroid Assay: no significant reduction in thyroid hormones in pups despite notable effects in dams.

Journal: The Journal of toxicological sciences

Published: November 04, 2024

Optimal testing time for cerebral heterotopia formation in the rat comparative thyroid assay, a downstream indicator for perinatal thyroid hormone insufficiency.

Optimal testing time for cerebral heterotopia formation in the rat comparative thyroid assay, a downstream indicator for perinatal thyroid hormone insufficiency.

Journal: Journal of toxicologic pathology

Published: January 17, 2024

Prenatal test cohort of a modified rat comparative thyroid assay adding brain thyroid hormone measurements and histology but lowering group size appears able to detect disruption by sodium phenobarbital.

Prenatal test cohort of a modified rat comparative thyroid assay adding brain thyroid hormone measurements and histology but lowering group size appears able to detect disruption by sodium phenobarbital.

Journal: Current research in toxicology

Published: December 13, 2023

Prediction of methane emissions from fattening cattle using the methane-to-carbon dioxide ratio.

Prediction of methane emissions from fattening cattle using the methane-to-carbon dioxide ratio.

Journal: Animal science journal = Nihon chikusan Gakkaiho

Published: December 06, 2022

Intramuscular adipogenesis in cattle: Effects of body fat distribution and macrophage infiltration.

Intramuscular adipogenesis in cattle: Effects of body fat distribution and macrophage infiltration.

Journal: Animal science journal = Nihon chikusan Gakkaiho

Published: August 25, 2022

Response to Letter to the Editor from Drs. van Kesteren, Pronk, Heusinkveld, Luijten and Hakkert concerning Yamada et al. (2021): Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Crit. Rev. Toxicol. Vol. 51: 373-394.

Response to Letter to the Editor from Drs. van Kesteren, Pronk, Heusinkveld, Luijten and Hakkert concerning Yamada et al. (2021): Critical evaluation of the human relevance of the mode of action for rodent liver tumor formation by activators of the constitutive androstane receptor (CAR). Crit. Rev. Toxicol. Vol. 51: 373-394.

Journal: Critical reviews in toxicology

Published: August 16, 2022

Feasibility study for a downsized comparative thyroid assay with measurement of brain thyroid hormones and histopathology in rats: Case study with 6-propylthiouracil and sodium phenobarbital at high dose.

Feasibility study for a downsized comparative thyroid assay with measurement of brain thyroid hormones and histopathology in rats: Case study with 6-propylthiouracil and sodium phenobarbital at high dose.

Journal: Regulatory toxicology and pharmacology : RTP

Published: June 14, 2022

Showing 1-12 of 50

Last Updated: 09/26/2026