Tomoyuki Isobe
Tokyo, Japan
Last Updated: 09/26/2026
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Found 8 publications
Liposome Encapsulation Enhances Ripasudil Therapeutic Efficacy Against Proliferative Vitreoretinal Diseases: Implications in Advanced Ocular Treatment.
Journal: Investigative ophthalmology & visual science
Published: June 17, 2025
Crossover Randomized Study of Pharmacologic Effects of Ripasudil-Brimonidine Fixed-Dose Combination Versus Ripasudil or Brimonidine.
Journal: Advances in therapy
Published: February 16, 2023
Additive Intraocular Pressure-Lowering Effects of Ripasudil with Glaucoma Therapeutic Agents in Rabbits and Monkeys.
Journal: Journal of ophthalmology
Published: December 28, 2016
Ocular Penetration and Pharmacokinetics of Ripasudil Following Topical Administration to Rabbits.
Journal: Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
Published: July 28, 2016
Vascular Normalization by ROCK Inhibitor: Therapeutic Potential of Ripasudil (K-115) Eye Drop in Retinal Angiogenesis and Hypoxia.
Journal: Investigative ophthalmology & visual science
Published: April 29, 2016
Species differences in metabolism of ripasudil (K-115) are attributed to aldehyde oxidase.
Journal: Xenobiotica; the fate of foreign compounds in biological systems
Published: December 19, 2015
Effects of K-115, a rho-kinase inhibitor, on aqueous humor dynamics in rabbits.
Journal: Current eye research
Published: February 08, 2014
Showing 1-8 of 8
Last Updated: 09/26/2026