Toru Komatsu

Hongo, 1130033, Japan

Last Updated: 09/26/2026

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Found 76 publications

Development of a series of catechol-containing xanthene fluorophores and their application to detect S-adenosylmethionine (SAM) utilizing catechol-O-methyltransferase (COMT) activities.

Development of a series of catechol-containing xanthene fluorophores and their application to detect S-adenosylmethionine (SAM) utilizing catechol-O-methyltransferase (COMT) activities.

Journal: Chemical communications (Cambridge, England)

Published: September 07, 2026

Synthesis Based on Covalent Capture and Release Enables Purification-free Fluorogenic Probe Libraries for Single-Molecule Protease Activity Profiling.

Synthesis Based on Covalent Capture and Release Enables Purification-free Fluorogenic Probe Libraries for Single-Molecule Protease Activity Profiling.

Journal: ACS central science

Published: May 04, 2026

Chemical basis of fluorogenic substrate probe design: revisiting the past to discover the new in biochemistry.

Chemical basis of fluorogenic substrate probe design: revisiting the past to discover the new in biochemistry.

Journal: RSC chemical biology

Published: April 06, 2026

Development of Single-Molecule Enzyme Activity Assay for Serine Hydrolases Using Activity-Based Protein Labeling Probes.

Development of Single-Molecule Enzyme Activity Assay for Serine Hydrolases Using Activity-Based Protein Labeling Probes.

Journal: Small methods

Published: August 25, 2025

Establishment of Single-molecule Enzyme Activity Profiling (SEAP) Platform by Hybrid Technologies of Chemical Biology and Biophysics

Establishment of Single-molecule Enzyme Activity Profiling (SEAP) Platform by Hybrid Technologies of Chemical Biology and Biophysics

Journal: Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan

Published: June 01, 2025

Mechanisms of histopathologic vascular damage caused by pancreatic juice leakage: Implications for preventing hemorrhagic complications.

Mechanisms of histopathologic vascular damage caused by pancreatic juice leakage: Implications for preventing hemorrhagic complications.

Journal: Surgery

Published: April 17, 2025

Application of Intramolecular O-to-N Phosphoryl Transfer Reaction to Design Fluorogenic Probes to Detect Activities of Enzymes That Metabolize Short Peptides and Acylamino Acids.

Application of Intramolecular O-to-N Phosphoryl Transfer Reaction to Design Fluorogenic Probes to Detect Activities of Enzymes That Metabolize Short Peptides and Acylamino Acids.

Journal: ACS sensors

Published: February 04, 2025

Single-Molecule Enzyme Activity Analysis for Illuminating Pathological Proteoforms.

Single-Molecule Enzyme Activity Analysis for Illuminating Pathological Proteoforms.

Journal: ACS central science

Published: January 17, 2025

γ-Secretase Cleaves Bifunctional Fatty Acid-Conjugated Small Molecules with Amide Bonds in Mammalian Cells.

γ-Secretase Cleaves Bifunctional Fatty Acid-Conjugated Small Molecules with Amide Bonds in Mammalian Cells.

Journal: ACS chemical biology

Published: November 20, 2024

Development of a near-infrared fluorescent probe for the selective detection of severe hypoxia.

Development of a near-infrared fluorescent probe for the selective detection of severe hypoxia.

Journal: RSC chemical biology

Published: October 07, 2024

Identification of a pancreatic juice-specific fluorescent probe through 411 probes activated by aminopeptidases/proteases or phosphatases/phosphodiesterases.

Identification of a pancreatic juice-specific fluorescent probe through 411 probes activated by aminopeptidases/proteases or phosphatases/phosphodiesterases.

Journal: HPB : the official journal of the International Hepato Pancreato Biliary Association

Published: September 01, 2024

A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT).

A general fluorescence off/on strategy for fluorogenic probes: Steric repulsion-induced twisted intramolecular charge transfer (sr-TICT).

Journal: Science advances

Published: February 16, 2024

Showing 1-12 of 76

Last Updated: 09/26/2026