Toshihito Isono

Niigata, Japan

Last Updated: 09/26/2026

Save publications for later
Sign Up
Not sure about your diagnosis?
Check Your Symptoms
Found 25 publications

Extracellular pneumolysin enhances the activation of cytosolic pattern-recognition receptor NOD2 through its pore-forming activity.

Extracellular pneumolysin enhances the activation of cytosolic pattern-recognition receptor NOD2 through its pore-forming activity.

Journal: Microbiology spectrum
Published: July 14, 2026

Increased Levels of High Mobility Group Box 1 in the Bronchoalveolar Lavage Fluid of Murine Pneumococcal Pneumonia Model.

Increased Levels of High Mobility Group Box 1 in the Bronchoalveolar Lavage Fluid of Murine Pneumococcal Pneumonia Model.

Journal: Microbiology and immunology
Published: January 16, 2026

Effective degradation of various bacterial toxins using ozone ultrafine bubble water.

Effective degradation of various bacterial toxins using ozone ultrafine bubble water.

Journal: PloS one
Published: March 28, 2024

Secretory leucocyte protease inhibitor regulates bone metabolism and inflammation in experimental mouse periodontitis.

Secretory leucocyte protease inhibitor regulates bone metabolism and inflammation in experimental mouse periodontitis.

Journal: Communications biology
Published: December 25, 2023

The Pneumococcal Protein SufC Binds to Host Plasminogen and Promotes Its Conversion into Plasmin.

The Pneumococcal Protein SufC Binds to Host Plasminogen and Promotes Its Conversion into Plasmin.

Journal: Microorganisms
Published: November 24, 2023

Lipoprotein signal peptidase-deficient Streptococcus pneumoniae exhibits impaired Toll-like receptor 2-stimulatory activity.

Lipoprotein signal peptidase-deficient Streptococcus pneumoniae exhibits impaired Toll-like receptor 2-stimulatory activity.

Journal: Microbiology and immunology
Published: October 27, 2023

A novel macrolide-Del-1 axis to regenerate bone in old age.

A novel macrolide-Del-1 axis to regenerate bone in old age.

Journal: iScience
Published: September 15, 2023

Pneumococcus downregulates the molecular weight of the extracellular domain of the epidermal growth factor receptor of alveolar epithelial cells.

Pneumococcus downregulates the molecular weight of the extracellular domain of the epidermal growth factor receptor of alveolar epithelial cells.

Journal: Microbiology and immunology
Published: July 11, 2023

Macrolides Decrease the Proinflammatory Activity of Macrolide-Resistant Streptococcus pneumoniae.

Macrolides Decrease the Proinflammatory Activity of Macrolide-Resistant Streptococcus pneumoniae.

Journal: Microbiology spectrum
Published: May 16, 2023

Erythromycin Restores Osteoblast Differentiation and Osteogenesis Suppressed by Porphyromonas gingivalis Lipopolysaccharide.

Erythromycin Restores Osteoblast Differentiation and Osteogenesis Suppressed by Porphyromonas gingivalis Lipopolysaccharide.

Journal: Pharmaceuticals (Basel, Switzerland)
Published: January 14, 2023

Degradation of EGFR on lung epithelial cells by neutrophil elastase contributes to the aggravation of pneumococcal pneumonia.

Degradation of EGFR on lung epithelial cells by neutrophil elastase contributes to the aggravation of pneumococcal pneumonia.

Journal: The Journal of biological chemistry
Published: December 29, 2022

Osteoimmunology in Periodontitis: Local Proteins and Compounds to Alleviate Periodontitis.

Osteoimmunology in Periodontitis: Local Proteins and Compounds to Alleviate Periodontitis.

Journal: International journal of molecular sciences
Published: April 16, 2022
Showing 1-12 of 25

Last Updated: 09/26/2026