Toshiyuki Shimizu
Tokyo, Japan
Last Updated: 09/26/2026
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Found 118 publications
2'-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity.
Journal: Nature immunology
Published: June 06, 2025
Mechanistic insights into single-stranded DNA degradation by lysosomal exonucleases PLD3 and PLD4 from structural snapshots.
Journal: Nature communications
Published: June 06, 2025
Anti-human TLR7 antibody for therapeutic intervention in systemic lupus erythematosus.
Journal: International immunology
Published: April 17, 2025
The pyrin domain of IFI16 forms a distinct filament structure important for IFI16-mediated enhancement of STING activation.
Journal: Structure (London, England : 1993)
Published: January 30, 2025
Recent advances in structural studies of NLRP3 and NLRP1 inflammasome regulation.
Journal: Current opinion in structural biology
Published: December 22, 2024
Architecture of the high-affinity immunoglobulin E receptor.
Journal: Science signaling
Published: December 10, 2024
Synergistic Activation of TLR7 and 8 Mediated by Reduction of Electrostatic Repulsion.
Journal: Chemical & pharmaceutical bulletin
Published: November 27, 2024
Structural insights into Wnt/β-catenin signaling regulation by LGR4, R-spondin, and ZNRF3.
Journal: Nature communications
Published: October 31, 2024
Structural Perspective of the Double-Stranded RNA Transport Mechanism by SID-1 Family Proteins.
Journal: Biological & pharmaceutical bulletin
Published: October 02, 2024
Lateral Wall Displacement of Calcaneal Fracture Leading to Peroneal Tendon Dislocation: Effect of the Distance of Lateral Wall Displacement on the incidence of Peroneal Tendon Dislocation.
Journal: The Journal of foot and ankle surgery : official publication of the American College of Foot and Ankle Surgeons
Published: August 05, 2024
Last Updated: 09/26/2026