Trevor D. Littlewood

Robinson Way
Cambridge, ENG, United Kingdom

Last Updated: 09/26/2026

Save publications for later

Sign Up

Not sure about your diagnosis?

Check Your Symptoms

Found 24 publications

HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes.

HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes.

Journal: Frontiers in cardiovascular medicine

Published: May 19, 2022

Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK.

Assembly of nuclear dimers of PI3K regulatory subunits is regulated by the Cdc42-activated tyrosine kinase ACK.

Journal: The Journal of biological chemistry

Published: March 07, 2022

Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution.

Reversible Myc hypomorphism identifies a key Myc-dependency in early cancer evolution.

Journal: Nature communications

Published: August 06, 2021

Methods for Determining Myc-Induced Apoptosis.

Methods for Determining Myc-Induced Apoptosis.

Journal: Methods in molecular biology (Clifton, N.J.)

Published: May 21, 2021

Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling.

Heterogeneity of Myc expression in breast cancer exposes pharmacological vulnerabilities revealed through executable mechanistic modeling.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: October 16, 2019

Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.

Reactivation of Myc transcription in the mouse heart unlocks its proliferative capacity.

Journal: Nature communications

Published: May 29, 2019

MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.

MYC Instructs and Maintains Pancreatic Adenocarcinoma Phenotype.

Journal: Cancer discovery

Published: April 17, 2019

Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells.

Tissue Inhibitor of Metalloproteinase-3 (TIMP-3) induces FAS dependent apoptosis in human vascular smooth muscle cells.

Journal: PloS one

Published: November 22, 2017

FOXO3a (Forkhead Transcription Factor O Subfamily Member 3a) Links Vascular Smooth Muscle Cell Apoptosis, Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway Involving MMP13 (Matrix Metalloproteinase 13).

FOXO3a (Forkhead Transcription Factor O Subfamily Member 3a) Links Vascular Smooth Muscle Cell Apoptosis, Matrix Breakdown, Atherosclerosis, and Vascular Remodeling Through a Novel Pathway Involving MMP13 (Matrix Metalloproteinase 13).

Journal: Arteriosclerosis, thrombosis, and vascular biology

Published: August 30, 2017

Determination of the physiological and pathological roles of E2F3 in adult tissues.

Determination of the physiological and pathological roles of E2F3 in adult tissues.

Journal: Scientific reports

Published: March 31, 2017

Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.

Myc Cooperates with Ras by Programming Inflammation and Immune Suppression.

Journal: Cell

Published: February 24, 2017

SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.

SOX2 Drives Bronchial Dysplasia in a Novel Organotypic Model of Early Human Squamous Lung Cancer.

Journal: American journal of respiratory and critical care medicine

Published: February 16, 2017

Showing 1-12 of 24

Last Updated: 09/26/2026