Trevor N. Johnson

John Street
Sheffield, ENG, United Kingdom

Last Updated: 09/26/2026

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Found 79 publications

Determining the comparative pharmacodynamic equivalence of a non-invasive diagnostic test for patients with adrenal insufficiency using a randomised 2-way crossover trial: the STARLIT-3 study protocol.

Determining the comparative pharmacodynamic equivalence of a non-invasive diagnostic test for patients with adrenal insufficiency using a randomised 2-way crossover trial: the STARLIT-3 study protocol.

Journal: BMJ open

Published: February 05, 2026

The rational use of PBPK to assess the changing DDI liability in pediatrics: Model qualification and the move towards best practice.

The rational use of PBPK to assess the changing DDI liability in pediatrics: Model qualification and the move towards best practice.

Journal: Drug metabolism and pharmacokinetics

Published: September 29, 2025

Development, Verification, and Application of a Chinese Pediatric Physiologically Based Pharmacokinetic Model: Emphasis on CYP Metabolism and Renal Elimination.

Development, Verification, and Application of a Chinese Pediatric Physiologically Based Pharmacokinetic Model: Emphasis on CYP Metabolism and Renal Elimination.

Journal: The AAPS journal

Published: May 15, 2025

Randomised, placebo-controlled, double-blinded, four-way crossover trial to demonstrate the comparative pharmacodynamic equivalence of a non-invasive diagnostic test for adrenal insufficiency in a healthy population: the STARLIT-2 study protocol.

Randomised, placebo-controlled, double-blinded, four-way crossover trial to demonstrate the comparative pharmacodynamic equivalence of a non-invasive diagnostic test for adrenal insufficiency in a healthy population: the STARLIT-2 study protocol.

Journal: BMJ open

Published: January 14, 2025

A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator.

A guide to developing population files for physiologically-based pharmacokinetic modeling in the Simcyp Simulator.

Journal: CPT: pharmacometrics & systems pharmacology

Published: March 11, 2024

Prediction of Pediatric Pharmacokinetics for CYP3A4 Metabolized Drugs: Comparison of the Performance of Two Hepatic Ontogeny Within a Physiologically Based Pharmacokinetic Model.

Prediction of Pediatric Pharmacokinetics for CYP3A4 Metabolized Drugs: Comparison of the Performance of Two Hepatic Ontogeny Within a Physiologically Based Pharmacokinetic Model.

Journal: Journal of clinical pharmacology

Published: February 27, 2024

Forecasting Fetal Buprenorphine Exposure through Maternal-Fetal Physiologically Based Pharmacokinetic Modeling.

Forecasting Fetal Buprenorphine Exposure through Maternal-Fetal Physiologically Based Pharmacokinetic Modeling.

Journal: Pharmaceutics

Published: February 13, 2024

Combining data on the bioavailability of midazolam and physiologically-based pharmacokinetic modeling to investigate intestinal CYP3A4 ontogeny.

Combining data on the bioavailability of midazolam and physiologically-based pharmacokinetic modeling to investigate intestinal CYP3A4 ontogeny.

Journal: CPT: pharmacometrics & systems pharmacology

Published: February 01, 2024

Development and Verification of a Full Physiologically Based Pharmacokinetic Model for Sublingual Buprenorphine in Healthy Adult Volunteers that Accounts for Nonlinear Bioavailability.

Development and Verification of a Full Physiologically Based Pharmacokinetic Model for Sublingual Buprenorphine in Healthy Adult Volunteers that Accounts for Nonlinear Bioavailability.

Journal: Drug metabolism and disposition: the biological fate of chemicals

Published: January 03, 2024

Demystifying physiologically based pharmacokinetic modelling among non-modelers towards model-informed medicine use in under-served populations.

Demystifying physiologically based pharmacokinetic modelling among non-modelers towards model-informed medicine use in under-served populations.

Journal: Gates open research

Published: September 29, 2023

Physiologically Based Pharmacokinetics Modeling in the Neonatal Population-Current Advances, Challenges, and Opportunities.

Physiologically Based Pharmacokinetics Modeling in the Neonatal Population-Current Advances, Challenges, and Opportunities.

Journal: Pharmaceutics

Published: September 26, 2023

Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.

Incorporation and Performance Verification of Hepatic Portal Blood Flow Shunting in Minimal and Full PBPK Models of Liver Cirrhosis.

Journal: Clinical pharmacology and therapeutics

Published: June 01, 2023

Showing 1-12 of 79

Last Updated: 09/26/2026