Trijnie Bos

Groningen, GR 9713GZ, Netherlands

Last Updated: 09/26/2026

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Found 13 publications

Assessing Nutraceuticals for Hepatic Steatosis: A Standardized In Vitro Approach.

Assessing Nutraceuticals for Hepatic Steatosis: A Standardized In Vitro Approach.

Journal: Nutrients

Published: December 18, 2025

Hepatocyte-specific Cas9-mediated editing of G6pc and Slc37a4 elicits comparable biochemical and regulatory responses between glycogen storage disease (GSD) type Ia and Ib mice.

Hepatocyte-specific Cas9-mediated editing of G6pc and Slc37a4 elicits comparable biochemical and regulatory responses between glycogen storage disease (GSD) type Ia and Ib mice.

Journal: Molecular metabolism

Published: October 24, 2025

Hepatic glucokinase regulatory protein and carbohydrate response element binding protein attenuation reduce de novo lipogenesis but do not mitigate intrahepatic triglyceride accumulation in Aldob deficiency.

Hepatic glucokinase regulatory protein and carbohydrate response element binding protein attenuation reduce de novo lipogenesis but do not mitigate intrahepatic triglyceride accumulation in Aldob deficiency.

Journal: Molecular metabolism

Published: April 01, 2024

Hepatic ChREBP orchestrates intrahepatic carbohydrate metabolism to limit hepatic glucose 6-phosphate and glycogen accumulation in a mouse model for acute Glycogen Storage Disease type Ib.

Hepatic ChREBP orchestrates intrahepatic carbohydrate metabolism to limit hepatic glucose 6-phosphate and glycogen accumulation in a mouse model for acute Glycogen Storage Disease type Ib.

Journal: Molecular metabolism

Published: October 27, 2023

Precision-cut liver slices as an ex vivo model to assess impaired hepatic glucose production.

Precision-cut liver slices as an ex vivo model to assess impaired hepatic glucose production.

Journal: Communications biology

Published: October 23, 2023

Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia.

Normalization of hepatic ChREBP activity does not protect against liver disease progression in a mouse model for Glycogen Storage Disease type Ia.

Journal: Cancer & metabolism

Published: January 25, 2023

Modeling Phenotypic Heterogeneity of Glycogen Storage Disease Type 1a Liver Disease in Mice by Somatic CRISPR/CRISPR-associated protein 9-Mediated Gene Editing.

Modeling Phenotypic Heterogeneity of Glycogen Storage Disease Type 1a Liver Disease in Mice by Somatic CRISPR/CRISPR-associated protein 9-Mediated Gene Editing.

Journal: Hepatology (Baltimore, Md.)

Published: September 29, 2020

Impaired Very-Low-Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia.

Impaired Very-Low-Density Lipoprotein catabolism links hypoglycemia to hypertriglyceridemia in Glycogen Storage Disease type Ia.

Journal: Journal of inherited metabolic disease

Published: September 07, 2020

Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a.

Hepatic Carbohydrate Response Element Binding Protein Activation Limits Nonalcoholic Fatty Liver Disease Development in a Mouse Model for Glycogen Storage Disease Type 1a.

Journal: Hepatology (Baltimore, Md.)

Published: July 05, 2019

Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice.

Glucose-6-Phosphate Regulates Hepatic Bile Acid Synthesis in Mice.

Journal: Hepatology (Baltimore, Md.)

Published: August 27, 2018

Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.

Intestinal Farnesoid X Receptor Controls Transintestinal Cholesterol Excretion in Mice.

Journal: Gastroenterology

Published: June 20, 2016

Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice.

Hepatic farnesoid X-receptor isoforms α2 and α4 differentially modulate bile salt and lipoprotein metabolism in mice.

Journal: PloS one

Published: August 12, 2014

Showing 1-12 of 13

Last Updated: 09/26/2026