Tsuneo Imanaka

Kure, 7370112, Japan

Last Updated: 09/26/2026

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Found 35 publications

FLG249 Exhibits FXR Antagonist Activity by Inducing Dissociation of Both Corepressors and Coactivators from FXR.

FLG249 Exhibits FXR Antagonist Activity by Inducing Dissociation of Both Corepressors and Coactivators from FXR.

Journal: Biological & pharmaceutical bulletin

Published: July 16, 2025

Mitotic abnormalities and spindle assembly checkpoint inactivation in a cell model of Shwachman-Diamond syndrome with mutations in the Shwachman-Bodian-Diamond syndrome gene, 258+2T > C.

Mitotic abnormalities and spindle assembly checkpoint inactivation in a cell model of Shwachman-Diamond syndrome with mutations in the Shwachman-Bodian-Diamond syndrome gene, 258+2T > C.

Journal: Drug discoveries & therapeutics

Published: October 27, 2024

FXR Antagonist FLG249 Lowers Hepatic Triacylglycerol and Serum Cholesterol Level in High-Fat Diet-Induced Obese Mice.

FXR Antagonist FLG249 Lowers Hepatic Triacylglycerol and Serum Cholesterol Level in High-Fat Diet-Induced Obese Mice.

Journal: Biological & pharmaceutical bulletin

Published: August 13, 2024

SBDS Gene Mutation Increases ROS Production and Causes DNA Damage as Well as Oxidation of Mitochondrial Membranes in the Murine Myeloid Cell Line 32Dcl3.

SBDS Gene Mutation Increases ROS Production and Causes DNA Damage as Well as Oxidation of Mitochondrial Membranes in the Murine Myeloid Cell Line 32Dcl3.

Journal: Biological & pharmaceutical bulletin

Published: July 31, 2024

M phase-specific interaction between SBDS and RNF2 at the mitotic spindles regulates mitotic progression.

M phase-specific interaction between SBDS and RNF2 at the mitotic spindles regulates mitotic progression.

Journal: Biochemical and biophysical research communications

Published: September 20, 2023

Transmembrane helix 6 of ABCD4 is indispensable for cobalamin transport.

Transmembrane helix 6 of ABCD4 is indispensable for cobalamin transport.

Journal: Journal of inherited metabolic disease

Published: August 26, 2023

Behavior of intracellular lipid droplets during cell division in HuH7 hepatoma cells.

Behavior of intracellular lipid droplets during cell division in HuH7 hepatoma cells.

Journal: Experimental cell research

Published: June 23, 2023

Substrate Specificity and the Direction of Transport in the ABC Transporters ABCD1-3 and ABCD4.

Substrate Specificity and the Direction of Transport in the ABC Transporters ABCD1-3 and ABCD4.

Journal: Chemical & pharmaceutical bulletin

Published: July 31, 2022

SBDS interacts with RNF2 and is degraded through RNF2-dependent ubiquitination.

SBDS interacts with RNF2 and is degraded through RNF2-dependent ubiquitination.

Journal: Biochemical and biophysical research communications

Published: January 25, 2022

The lysosomal protein ABCD4 can transport vitamin B12 across liposomal membranes in vitro.

The lysosomal protein ABCD4 can transport vitamin B12 across liposomal membranes in vitro.

Journal: The Journal of biological chemistry

Published: September 24, 2020

Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2KbtsA58 mice to facilitate the study of the role of astrocytes in X-linked adrenoleukodystrophy.

Generation of an immortalized astrocytic cell line from Abcd1-deficient H-2KbtsA58 mice to facilitate the study of the role of astrocytes in X-linked adrenoleukodystrophy.

Journal: Heliyon

Published: September 19, 2020

Bone marrow transplantation into Abcd1-deficient mice: Distribution of donor derived-cells and biological characterization of the brain of the recipient mice.

Bone marrow transplantation into Abcd1-deficient mice: Distribution of donor derived-cells and biological characterization of the brain of the recipient mice.

Journal: Journal of inherited metabolic disease

Published: August 29, 2020

Showing 1-12 of 35

Last Updated: 09/26/2026