Umeharu Ohto
Tokyo, Japan
Last Updated: 09/26/2026
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Found 74 publications
2'-O-Methyl-guanosine RNA fragments antagonize TLR7 and TLR8 to limit autoimmunity.
Journal: Nature immunology
Published: June 06, 2025
Mechanistic insights into single-stranded DNA degradation by lysosomal exonucleases PLD3 and PLD4 from structural snapshots.
Journal: Nature communications
Published: June 06, 2025
Multistep receptor binding of the hepatitis B virus preS1 domain.
Journal: Nature communications
Published: June 03, 2025
The pyrin domain of IFI16 forms a distinct filament structure important for IFI16-mediated enhancement of STING activation.
Journal: Structure (London, England : 1993)
Published: January 30, 2025
Architecture of the high-affinity immunoglobulin E receptor.
Journal: Science signaling
Published: December 10, 2024
Synergistic Activation of TLR7 and 8 Mediated by Reduction of Electrostatic Repulsion.
Journal: Chemical & pharmaceutical bulletin
Published: November 27, 2024
Structural insights into Wnt/β-catenin signaling regulation by LGR4, R-spondin, and ZNRF3.
Journal: Nature communications
Published: October 31, 2024
Dexmedetomidine directly binds to and inhibits Toll-like receptor 4.
Journal: International immunopharmacology
Published: July 23, 2024
Targeting toll-like receptor 7 as a therapeutic development strategy for systemic lupus erythematosus.
Journal: Acta pharmaceutica Sinica. B
Published: April 27, 2024
A coronavirus assembly inhibitor that targets the viral membrane protein.
Journal: Nature
Published: April 06, 2024
The structures of the peptide transporters SLC15A3 and SLC15A4 reveal the recognition mechanisms for substrate and TASL.
Journal: Structure (London, England : 1993)
Published: January 18, 2024
Last Updated: 09/26/2026