Uwe Jerke
Berlin, BE, Germany
Last Updated: 09/26/2026
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Found 13 publications
Towards a proteomic plasma biomarker panel for diagnosing vasculitis remission.
Journal: Nature communications
Published: September 16, 2025
CRISPR-Cas9 mediated proteinase 3 autoantigen deletion as a treatment strategy for anti-neutrophil cytoplasmic autoantibody-associated vasculitis.
Journal: Kidney international
Published: February 25, 2025
β2-integrins control HIF1α activation in human neutrophils.
Journal: Frontiers in immunology
Published: March 25, 2024
Pharmacological inhibition of cathepsin S and of NSPs-AAP-1 (a novel, alternative protease driving the activation of neutrophil serine proteases).
Journal: Biochemical pharmacology
Published: November 09, 2023
Protective α1-antitrypsin effects in autoimmune vasculitis are compromised by methionine oxidation.
Journal: The Journal of clinical investigation
Published: March 11, 2022
Competitively disrupting the neutrophil-specific receptor-autoantigen CD177:proteinase 3 membrane complex reduces anti-PR3 antibody-induced neutrophil activation.
Journal: The Journal of biological chemistry
Published: September 03, 2021
Targeting Cathepsin C in PR3-ANCA Vasculitis.
Journal: Journal of the American Society of Nephrology : JASN
Published: August 20, 2021
Neutrophil Gelatinase-Associated Lipocalin Protects from ANCA-Induced GN by Inhibiting TH17 Immunity.
Journal: Journal of the American Society of Nephrology : JASN
Published: September 05, 2019
Consequences of cathepsin C inactivation for membrane exposure of proteinase 3, the target antigen in autoimmune vasculitis.
Journal: The Journal of biological chemistry
Published: January 16, 2018
Characterization of the CD177 interaction with the ANCA antigen proteinase 3.
Journal: Scientific reports
Published: July 04, 2016
Lessons from a double-transgenic neutrophil approach to induce antiproteinase 3 antibody-mediated vasculitis in mice.
Journal: Journal of leukocyte biology
Published: January 22, 2016
Neutrophil serine proteases exert proteolytic activity on endothelial cells.
Journal: Kidney international
Published: January 21, 2015
Last Updated: 09/26/2026