Vanessa Tatangelo

Via Aldo Moro 2
Siena, 53100, Italy

Last Updated: 09/26/2026

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Found 11 publications

Taginostat, a new quinolone-based HDAC6 inhibitor, promotes apoptosis of chronic lymphocytic leukemia cells in vitro and in vivo by activating STAT4.

Taginostat, a new quinolone-based HDAC6 inhibitor, promotes apoptosis of chronic lymphocytic leukemia cells in vitro and in vivo by activating STAT4.

Journal: Apoptosis : an international journal on programmed cell death

Published: December 02, 2025

Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles.

Activation-induced thrombospondin-4 works with thrombospondin-1 to build cytotoxic supramolecular attack particles.

Journal: Proceedings of the National Academy of Sciences of the United States of America

Published: February 04, 2025

Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy.

Rewiring the T cell-suppressive cytokine landscape of the tumor microenvironment: a new frontier for precision anti-cancer therapy.

Journal: Frontiers in immunology

Published: April 16, 2024

A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients.

A novel potent class I HDAC inhibitor reverses the STAT4/p66Shc apoptotic defect in B cells from chronic lymphocytic leukemia patients.

Journal: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie

Published: January 12, 2024

p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation.

p66Shc deficiency in CLL cells enhances PD-L1 expression and suppresses immune synapse formation.

Journal: Frontiers in cell and developmental biology

Published: September 19, 2023

Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia.

Leukemic cell-secreted interleukin-9 suppresses cytotoxic T cell-mediated killing in chronic lymphocytic leukemia.

Journal: Cell death & disease

Published: May 16, 2023

Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.

Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability.

Journal: European journal of medicinal chemistry

Published: February 21, 2022

p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB.

p66Shc Deficiency in Chronic Lymphocytic Leukemia Promotes Chemokine Receptor Expression Through the ROS-Dependent Inhibition of NF-κB.

Journal: Frontiers in oncology

Published: February 16, 2022

Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation.

Glycerophosphoinositol Promotes Apoptosis of Chronic Lymphocytic Leukemia Cells by Enhancing Bax Expression and Activation.

Journal: Frontiers in oncology

Published: December 14, 2021

Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment.

Enhanced IL-9 secretion by p66Shc-deficient CLL cells modulates the chemokine landscape of the stromal microenvironment.

Journal: Blood

Published: March 11, 2020

Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays.

Optimization of Organotypic Cultures of Mouse Spleen for Staining and Functional Assays.

Journal: Frontiers in immunology

Published: November 26, 2019

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Last Updated: 09/26/2026