Vendula Hepnarova

Hradec Kralove, KR 50001, Czech Republic

Last Updated: 09/26/2026

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Found 29 publications

Next-generation broad-spectrum reactivators for effective countermeasure against organophosphorus poisoning.

Next-generation broad-spectrum reactivators for effective countermeasure against organophosphorus poisoning.

Journal: Archives of toxicology

Published: October 29, 2025

A-series agent A-234: initial in vitro and in vivo characterization.

A-series agent A-234: initial in vitro and in vivo characterization.

Journal: Archives of toxicology

Published: January 05, 2024

Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication.

Uncharged mono- and bisoximes: In search of a zwitterion to countermeasure organophosphorus intoxication.

Journal: Chemico-biological interactions

Published: January 02, 2024

A-agents, misleadingly known as "Novichoks": a narrative review.

A-agents, misleadingly known as "Novichoks": a narrative review.

Journal: Archives of toxicology

Published: July 11, 2023

Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.

Structure-Guided Design of N-Methylpropargylamino-Quinazoline Derivatives as Multipotent Agents for the Treatment of Alzheimer's Disease.

Journal: International journal of molecular sciences

Published: May 08, 2023

Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides.

Non-covalent acetylcholinesterase inhibitors: In vitro screening and molecular modeling for novel selective insecticides.

Journal: Toxicology in vitro : an international journal published in association with BIBRA

Published: June 13, 2022

A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats.

A Comparison of the Neuroprotective and Reactivating Efficacy of a Novel Bispyridinium Oxime K870 with Commonly Used Pralidoxime and the Oxime HI-6 in Tabun-Poisoned Rats.

Journal: Acta medica (Hradec Kralove)

Published: November 15, 2021

Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870.

Toxicity, pharmacokinetics, and effectiveness of the ortho-chlorinated bispyridinium oxime, K870.

Journal: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Published: September 07, 2021

Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.

Phenothiazine-Tacrine Heterodimers: Pursuing Multitarget Directed Approach in Alzheimer's Disease.

Journal: ACS chemical neuroscience

Published: April 14, 2021

Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease.

Design and synthesis of novel tacrine-indole hybrids as potential multitarget-directed ligands for the treatment of Alzheimer's disease.

Journal: Future medicinal chemistry

Published: April 08, 2021

(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.

(±)-BIGI-3h: Pentatarget-Directed Ligand combining Cholinesterase, Monoamine Oxidase, and Glycogen Synthase Kinase 3β Inhibition with Calcium Channel Antagonism and Antiaggregating Properties for Alzheimer's Disease.

Journal: ACS chemical neuroscience

Published: April 02, 2021

Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.

Huprine Y - Tryptophan heterodimers with potential implication to Alzheimer's disease treatment.

Journal: Bioorganic & medicinal chemistry letters

Published: February 12, 2021

Showing 1-12 of 29

Last Updated: 09/26/2026