Vincent Van Den Boom

Groningen, GR 9713GZ, Netherlands

Last Updated: 09/26/2026

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Found 13 publications

Sustained PRC1.1 activity preserves gene repression independently of PRC2.2 and restrains leukemic cell differentiation.

Sustained PRC1.1 activity preserves gene repression independently of PRC2.2 and restrains leukemic cell differentiation.

Journal: Nucleic acids research
Published: July 09, 2025

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia.

ΔNp73 isoform defines a TP53-mutant-like poor-risk subgroup of acute myeloid leukemia.

Journal: Cell reports. Medicine
Published: March 04, 2025

Bleximenib, the novel menin-KMT2A inhibitor JNJ-75276617, impairs long-term proliferation and immune evasion in acute myeloid leukemia.

Bleximenib, the novel menin-KMT2A inhibitor JNJ-75276617, impairs long-term proliferation and immune evasion in acute myeloid leukemia.

Journal: Haematologica
Published: April 16, 2024

Dietary methionine starvation impairs acute myeloid leukemia progression.

Dietary methionine starvation impairs acute myeloid leukemia progression.

Journal: Blood
Published: June 27, 2022

The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia.

The USP7-TRIM27 axis mediates non-canonical PRC1.1 function and is a druggable target in leukemia.

Journal: iScience
Published: November 25, 2020

Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock.

Protein quality control in the nucleolus safeguards recovery of epigenetic regulators after heat shock.

Journal: eLife
Published: January 15, 2019

HSCs: they can't live without their SINs.

HSCs: they can't live without their SINs.

Journal: Blood
Published: January 07, 2017

Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis.

Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis.

Journal: Cell reports
Published: October 07, 2015

Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins.

Conservation of inner nuclear membrane targeting sequences in mammalian Pom121 and yeast Heh2 membrane proteins.

Journal: Molecular biology of the cell
Published: March 31, 2015

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2.

Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2.

Journal: PloS one
Published: January 29, 2015

Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells.

Nonredundant and locus-specific gene repression functions of PRC1 paralog family members in human hematopoietic stem/progenitor cells.

Journal: Blood
Published: January 26, 2013

The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation.

The combination of valproic acid and lithium delays hematopoietic stem/progenitor cell differentiation.

Journal: Blood
Published: February 14, 2012
Showing 1-12 of 13

Last Updated: 09/26/2026