Vivien Grant

5 Little France Drive
Edinburgh, SCT EH164UU, United Kingdom

Last Updated: 09/26/2026

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Found 8 publications

RNA lipid nanoparticles as efficient in vivo CRISPR-Cas9 gene editing tool for therapeutic target validation in glioblastoma cancer stem cells.

RNA lipid nanoparticles as efficient in vivo CRISPR-Cas9 gene editing tool for therapeutic target validation in glioblastoma cancer stem cells.

Journal: Journal of controlled release : official journal of the Controlled Release Society

Published: May 03, 2024

Oncogene expression from extrachromosomal DNA is driven by copy number amplification and does not require spatial clustering in glioblastoma stem cells.

Oncogene expression from extrachromosomal DNA is driven by copy number amplification and does not require spatial clustering in glioblastoma stem cells.

Journal: eLife

Published: May 16, 2022

Elevated FOXG1 in glioblastoma stem cells cooperates with Wnt/β-catenin to induce exit from quiescence.

Elevated FOXG1 in glioblastoma stem cells cooperates with Wnt/β-catenin to induce exit from quiescence.

Journal: Cell reports

Published: May 10, 2022

Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants.

Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants.

Journal: Cell stem cell

Published: June 22, 2020

Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells.

Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells.

Journal: Nature genetics

Published: May 21, 2020

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.

Glioblastomas acquire myeloid-affiliated transcriptional programs via epigenetic immunoediting to elicit immune evasion.

Journal: Cell

Published: January 27, 2020

Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators.

Elevated FOXG1 and SOX2 in glioblastoma enforces neural stem cell identity through transcriptional control of cell cycle and epigenetic regulators.

Journal: Genes & development

Published: November 01, 2016

Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.

Efficient CRISPR/Cas9-assisted gene targeting enables rapid and precise genetic manipulation of mammalian neural stem cells.

Journal: Development (Cambridge, England)

Published: June 06, 2016

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Last Updated: 09/26/2026